Flamax forte, 100 mg 20 pcs

Flamax Forte is a non-steroidal anti-inflammatory drug, a derivative of propionic acid.

It has analgesic, anti-inflammatory and antipyretic effects, inhibits platelet aggregation.

Empacting on cyclooxygenase and lipooxygenase link of arachidonic acid metabolism, ketoprofen inhibits the synthesis of prostaglandins, leukotrienes and thromboxanes.

The analgesic effect is due to both central and peripheral mechanisms.

It has anti-bradykinin activity and stabilizes lysosomal membranes.

Indications

Inflammatory and degenerative diseases of the musculoskeletal system:

Pain syndrome:

Active ingredient

Composition

1 film-coated tablet contains 100 mg ketoprofen;

Associates:

lactose monohydrate,

rice starch,

croscarmellose sodium,

br>

povidone,

microcrystalline cellulose,

magnesium stearate,

sodium lauryl sulfate,

silicon dioxide colloid,

hypromellose,

macrogol 6000,

talc,

titanium dioxide,

brilliant blue.

How to take, the dosage

Adults administer Flamax forte orally in an initial daily dose of 300 mg in 2-3 doses.

The maximum daily dose is 300 mg.

Interaction

Reduces the effectiveness of uricosuric drugs, increases the effect of anticoagulants, antiaggregants, fibrinolytics, ethanol, the side effects of glucocorticosteroids and mineralocorticosteroids, estrogens; reduces the effectiveness of hypotensive drugs and diuretics.

Combination with other NSAIDs, glucocorticosteroids, ethanol, corticotropin may lead to ulceration and gastrointestinal bleeding, increased risk of renal dysfunction.

The simultaneous use with oral anticoagulants, heparin, thrombolytics, antiaggregants, cefaperazone, cefamandole and cefotetan increases the risk of bleeding.

Induces hypoglycemic effect of insulin and oral hypoglycemic drugs (recalculation of the dose is necessary). Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase production of hydroxylated active metabolites.

Co-administration with sodium valproate causes impairment of platelet aggregation.

Enhances plasma concentrations of verapamil and nifedipine, lithium drugs, methotrexate. Antacids and colestyramine reduce absorption.

Myelotoxic drugs increase manifestations of hematotoxicity of the drug.

Special Instructions

Special caution is exercised when prescribing Flamax forte in patients with liver and kidney diseases, gastrointestinal tract diseases and immediately after major surgical interventions.

In the course of treatment with the drug, systematic monitoring of liver and kidney function is necessary.

The simultaneous administration with anticoagulants increases the risk of bleeding.

Contraindications

Side effects

Overdose

Symptoms: drowsiness, nausea, vomiting, abdominal pain, bleeding, liver and kidney function disorders may occur.

The treatment is symptomatic: gastric lavage and/or activated charcoal and/or other sorbents. There is no specific antidote.

Pregnancy use

Flamax forte is contraindicated in pregnancy, lactation and children under the age of 15 years.

Similarities