Flamax Forte is a non-steroidal anti-inflammatory drug, a derivative of propionic acid.
It has analgesic, anti-inflammatory and antipyretic effects, inhibits platelet aggregation.
Empacting on cyclooxygenase and lipooxygenase link of arachidonic acid metabolism, ketoprofen inhibits the synthesis of prostaglandins, leukotrienes and thromboxanes.
The analgesic effect is due to both central and peripheral mechanisms.
It has anti-bradykinin activity and stabilizes lysosomal membranes.
Pain after injuries and operations, Neck pain, Gout, Back pain, Lumbago, Joint pain (arthralgia), Neuralgia, trigeminal neuralgia, Swelling after injuries and operations, Osteochondrosis, Bruises, Arthritis, Rheumatoid arthritis, Myalgia (muscle pain), Arthrosis, Myositis, Osteoarthritis, Bursitis, Sciatica
Inflammatory and degenerative diseases of the musculoskeletal system:
- rheumatoid, psoriatic arthritis,
- Bechterew’s disease (ankylosing spondylitis),
- gouty arthritis (in an acute attack of gout, quick-acting dosage forms are preferred),
- headache and toothache,
- in cancer,
- posttraumatic and postoperative pain syndrome accompanied by inflammation.
1 film-coated tablet contains 100 mg ketoprofen;
sodium lauryl sulfate,
silicon dioxide colloid,
How to take, the dosage
Adults administer Flamax forte orally in an initial daily dose of 300 mg in 2-3 doses.
The maximum daily dose is 300 mg.
Reduces the effectiveness of uricosuric drugs, increases the effect of anticoagulants, antiaggregants, fibrinolytics, ethanol, the side effects of glucocorticosteroids and mineralocorticosteroids, estrogens; reduces the effectiveness of hypotensive drugs and diuretics.
Combination with other NSAIDs, glucocorticosteroids, ethanol, corticotropin may lead to ulceration and gastrointestinal bleeding, increased risk of renal dysfunction.
The simultaneous use with oral anticoagulants, heparin, thrombolytics, antiaggregants, cefaperazone, cefamandole and cefotetan increases the risk of bleeding.
Induces hypoglycemic effect of insulin and oral hypoglycemic drugs (recalculation of the dose is necessary). Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase production of hydroxylated active metabolites.
Co-administration with sodium valproate causes impairment of platelet aggregation.
Enhances plasma concentrations of verapamil and nifedipine, lithium drugs, methotrexate. Antacids and colestyramine reduce absorption.
Myelotoxic drugs increase manifestations of hematotoxicity of the drug.
Special caution is exercised when prescribing Flamax forte in patients with liver and kidney diseases, gastrointestinal tract diseases and immediately after major surgical interventions.
In the course of treatment with the drug, systematic monitoring of liver and kidney function is necessary.
The simultaneous administration with anticoagulants increases the risk of bleeding.
- erosive ulcerative lesions of the gastrointestinal tract in the acute phase
- “aspirin” asthma
- explicit liver and/or kidney function disorders
- high sensitivity to Flamax forte, hemorrhoids to use suppositories, skin diseases and wounds to use the gel.
- constipation or diarrhea,
- allergic reactions in the form of skin rash
- erosive ulcerative lesions of the gastrointestinal tract
- bleeding of the gastrointestinal tract.
Symptoms: drowsiness, nausea, vomiting, abdominal pain, bleeding, liver and kidney function disorders may occur.
The treatment is symptomatic: gastric lavage and/or activated charcoal and/or other sorbents. There is no specific antidote.
Flamax forte is contraindicated in pregnancy, lactation and children under the age of 15 years.
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|Conditions of storage|
In a dry, light-protected place at a temperature not exceeding 25 °C
PharmFirm Sotex, Russia
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