Diclofenac, 1% ointment 30 g

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. It inhibits COX enzyme in the cascade of arachidonic acid metabolism and disrupts prostaglandin biosynthesis.

When used externally it has anti-inflammatory and analgesic effects.

Limits and relieves pain at the site of application of the ointment (including joint pain at rest and on movement), reduces morning stiffness and joint swelling. Helps to increase range of motion.

Indications

inflammatory and degenerative diseases of the joints (osteochondrosis, osteoarthritis, periarthropathy);
soft tissue rheumatism;
traumatic bruises;
sprains of ligaments, muscles and tendons;
inflammatory swelling of soft tissues;
arthralgia and myalgia caused by heavy physical activity.

Pharmacological effect

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. Inhibits the COX enzyme in the arachidonic acid metabolic cascade and disrupts the biosynthesis of prostaglandins.

When applied externally, it has an anti-inflammatory and analgesic effect.

Reduces and relieves pain at the site of application of the ointment (including pain in the joints at rest and during movement), reduces morning stiffness and swelling of the joints. Helps increase range of motion.

Special instructions

Apply externally only. The ointment can only be applied to intact areas of the skin. After applying the ointment, do not apply an occlusive dressing. Before use, patients with gastric and duodenal ulcers, impaired liver, kidney or hematopoietic function, as well as concomitant use of other non-steroidal anti-inflammatory drugs, should consult a doctor. When using the drug together with other dosage forms of diclofenac, the maximum daily dose should be taken into account.

With long-term use and/or application to large surfaces, systemic side effects may develop due to the resorptive effect. Avoid contact of the drug with the eyes, mucous membranes or open wounds.

Impact on the ability to drive vehicles and operate machinery

The drug does not affect the ability to drive a car or use other mechanical means.

Active ingredient

Diclofenac

Composition

Active substance: diclofenac sodium – 1.0 g;

Excipients: dimethyl sulfoxide – 10 g, macrogol-1500 – 30 g, macrogol-400 – 49 g, propylene glycol – 10 g.

Contraindications

Hypersensitivity to diclofenac.

Complete or incomplete combination of bronchial asthma, recurrent nasal polyposis and paranasal sinuses, and intolerance to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (including a history).

Pregnancy (III trimester), breastfeeding period, childhood (up to 12 years). Violation of the integrity of the skin at the intended site of application.

With caution:

Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe dysfunction of the liver and kidneys, chronic heart failure, bleeding disorders (including hemophilia, prolongation of bleeding time, tendency to bleed), old age, pregnancy I and II trimester.

Side Effects

The incidence of side effects is classified according to the recommendations of the World Health Organization: characterized as very common – at least 10%; often – at least 1%, but less than 10%; infrequently – not less than 0.1%, but less than 1%; rarely – not less than 0.01%, but less than 0.1%; very rare, including individual messages – less than 0.01%.

Local reactions: infrequently – exudative erythema multiforme (including Stevens-Johnson syndrome), eczema, very rarely – contact dermatitis (itching, hyperemia, swelling of the treated skin area, papular-vesicular rashes, peeling).

When applying the ointment to large surfaces of the skin over a long period of time, systemic side effects of diclofenac may develop.

Systemic reactions: rarely – generalized skin rash, allergic reactions (urticaria, angioedema, bronchospastic reactions), rarely photosensitivity, very rarely – anaphylactic reactions (including shock).

Interaction

The use of the drug with other non-steroidal anti-inflammatory drugs is not recommended.

Diclofenac may enhance the effect of drugs that cause photosensitivity.

Clinically significant interactions with other drugs have not been described.

Recommendations for use

Externally.

For adults and children over 12 years of age, the drug is applied to the skin 2 times a day (every 12 hours, preferably in the morning and evening), at a dose of 2-4 g. Apply a thin layer to the skin above the inflammation and rub in lightly.

The maximum daily dose of ointment should not exceed 8 g.

The course of treatment is no more than 14 days. The need for longer-term use of the drug is determined by the doctor.

If your hands are not the area where pain is localized, then after applying the ointment they should be washed.

Use in minimally effective doses for a minimally short course.

Storage conditions

At a temperature not exceeding 25 °C. (do not freeze).

Shelf life

2 years.

Manufacturer

Ozon, Russia