Cortexin, lyophilizate 5 mg 11 g 10 pcs

CORTEXIN contains a complex of low molecular weight water-soluble polypeptide fractions penetrating directly through the blood-brain barrier to the nerve cells. The product has nootropic, neuroprotective, antioxidant and tissue-specific effects. It improves higher brain functions, learning and memory processes, concentration of attention, resistance to various stress factors.

Neuroprotective – protects neurons from damage by various endogenous neurotoxic factors (glutamate, calcium ions, free radicals), reduces the toxic effects of psychotropic substances.Antioxidant – inhibits lipid peroxidation in neurons, increases the survival of neurons under oxidative stress and hypoxia. Tissue-specific – activates metabolism of central and peripheral nervous system neurons, reparative processes, improves cortical functions and overall tone of the nervous system.

Mechanism of action

CORTEXIN is due to activation of neuronal peptides and neurotrophic factors of the brain; optimization of the balance of metabolism of excitatory and inhibitory amino acids, dopamine, serotonin; GABAergic action; reduction of paroxysmal seizure activity of the brain, ability to improve its bioelectrical activity; prevention of free radical formation (products of lipid peroxidation).

Pharmacokinetics

The composition of CORTEXIN, the active substance of which is a complex of polypeptide fractions, does not allow the usual pharmacokinetic analysis of individual components.

Indications

In complex therapy:

cerebrovascular accident;
TBI and its consequences;
encephalopathy of various origins;
cognitive impairment (memory and thinking disorders);
acute and chronic encephalitis and encephalomyelitis;
epilepsy;
asthenic conditions (suprasegmental vegetative disorders);
reduced learning ability;
delayed psychomotor and speech development in children;
various forms of cerebral palsy.

Pharmacological effect

CORTEXIN contains a complex of low molecular weight water-soluble polypeptide fractions that penetrate the blood-brain barrier directly to nerve cells. The drug has nootropic, neuroprotective, antioxidant and tissue-specific effects. Nootropic – improves higher brain functions, learning and memory processes, concentration, and resistance to various stressful influences.

Neuroprotective – protects neurons from damage by various endogenous neurotoxic factors (glutamate, calcium ions, free radicals), reduces the toxic effects of psychotropic substances. Antioxidant – inhibits lipid peroxidation in neurons, increases the survival of neurons under conditions of oxidative stress and hypoxia. Tissue-specific – activates the metabolism of neurons of the central and peripheral nervous system, reparative processes, helps improve functions cerebral cortex and general tone of the nervous system.

Mechanism of action

CORTEXIN is caused by the activation of neuronal peptides and neurotrophic factors of the brain; optimization of the balance of metabolism of excitatory and inhibitory amino acids, dopamine, serotonin; GABAergic effects; a decrease in the level of paroxysmal convulsive activity of the brain, the ability to improve its bioelectrical activity; preventing the formation of free radicals (products of lipid peroxidation).

Pharmacokinetics

The composition of CORTEXIN, the active substance of which is a complex of polypeptide fractions, does not allow for conventional pharmacokinetic analysis of individual components.

Special instructions

Before use, it is recommended to consult a specialist.

Active ingredient

Livestock cerebral cortex polypeptides

Composition

1 bottle of lyophilisate contains:

Active ingredient:

cortexin (complex of water-soluble polypeptide fractions) 5 mg;

Excipient:

vglycine (stabilizer).

Pregnancy

Cortexin is contraindicated during pregnancy and lactation

Contraindications

The drug is contraindicated during pregnancy (due to the lack of clinical trial data).

If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped (due to the lack of clinical trial data).

Side Effects

There were no reports of side effects.

Individual hypersensitivity to the components of the drug is possible.

Interaction

No drug interactions have been described.

Overdose

Currently, no cases of drug overdose have been reported.

Storage conditions

The drug should be stored in a dry place, protected from light, at a temperature of 2° to 20°C.

Shelf life

2 years.

Manufacturer

Geropharm LLC, Russia