Cortexin, lyophilizate 10 mg 22 g 10 pcs

CORTEXIN contains a complex of low molecular weight water-soluble polypeptide fractions penetrating directly through the blood-brain barrier to the nerve cells. The product has nootropic, neuroprotective, antioxidant and tissue-specific effects. It improves higher brain functions, learning and memory processes, concentration of attention, resistance to various stress influences.

Neuroprotective – protects neurons from damage by various endogenous neurotoxic factors (glutamate, calcium ions, free radicals), reduces the toxic effects of psychotropic substances.

Antioxidant – inhibits lipid peroxidation in neurons, increases the survival of neurons in conditions of oxidative stress and hypoxia. Tissue-specific – activates the metabolism of central and peripheral nervous system neurons, repair processes, improves cortical functions and overall tonus of the nervous system.

Mechanism of action

CORTEXIN is due to activation of neuronal peptides and neurotrophic factors of the brain; optimization of the balance of metabolism of excitatory and inhibitory amino acids, dopamine, serotonin; GABAergic action; reduction of paroxysmal seizure activity of the brain, ability to improve its bioelectrical activity; prevention of free radical formation (products of lipid peroxidation).

Pharmacokinetics

The composition of CORTEXIN, whose active substance is a complex of polypeptide fractions, does not allow the usual pharmacokinetic analysis of individual components.

Indications

In complex therapy:

• brain circulation disorders;
• CMT and its consequences;
• encephalopathies of various genesis;
• cognitive disorders (memory and thinking disorders);
• acute and chronic encephalitis and encephalomyelitis;
epilepsy;
• asthenic conditions (suprasegmental autonomic disorders);
• disabled learning ability;
• delayed psychomotor and speech development in children;
• different forms of infantile cerebral palsy.

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Active ingredient

Polypeptides of the cortex of cattle

Composition

1 bottle of lyophilizate contains:

the active ingredient:

cortexin (complex of water-soluble polypeptide fractions) 10 mg,

complementary substance:

vglycin (stabilizer) 12 mg

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How to take, the dosage

The drug is administered intramuscularly.

If necessary, a repeated course in 3-6 months.In hemispheric ischemic stroke in the acute and early recovery periods, adults in a dose of 10 mg twice daily (morning and afternoon) for 10 days, with a repeat course in 10 days.

Contraindications

Individual intolerance to the drug.

The drug is contraindicated in pregnancy (due to the lack of clinical trial data).

Breast-feeding should be stopped if the drug has to be administered during lactation (due to the lack of data from clinical trials).

Side effects

There have been no reports of side effects.

Individual hypersensitivity to the components of the drug is possible.