Contraktubex, gel 20 g

Pharmacotherapeutic group: D03AX. Hyperrubbing treatment.

Pharmacological properties

Pharmacodynamics:
A combined drug whose action is due to the properties of its constituent components. It has a fibrinolytic anti-inflammatory effect (due to the presence of Sera extract), antithrombic (due to the presence of heparin) and keratolytic (due to the presence of allantoin). Stimulates cellular regeneration without hyperplasia. Inhibits the proliferation of kelloid fibroblasts.

Pharmacokinetics:
In the experiment it was shown that heparin for 4 hours in clinically sufficient amounts penetrates into the connective tissue of the dermis. Deep penetration is provided by the combination of heparin with extract of Serae bulbs and allantoin (transepidermal heparinization).
When using the drug Contraktubex systemic absorption is not observed.

Indications

Hypertrophic and keloid scars arising after surgical operations, amputations, burns and injuries
– Ankylosis (contractures) of the joints
– Dupuytren’s contracture
– Traumatic tendon contractures
– Stretch marks after pregnancy
– Atrophic scars (in particular those arising after aspiration or furunculosis)
– Prevention of pathological scars in the postoperative period or after an accident.
– Atrophic scars (especially after asp or furunculosis)
– Prevention of pathological scars in the post-operative period or after an accident

Can be used on children.

Active ingredient

Allantoin, Sodium Heparin, Onion Bulb Extract

Composition

Ingredients per 100 g gel

liquid onion bulb extract 10 g
sodium heparin 50000 ME
allantoin 1 g

Associates:
sorbic acid 0,1 g
methyl parahydroxybenzoate 0,15 g
xanthan gum (xanthral 75) 2 g
macrogoal 200 (polyethylene glycol 200) 25 g
aromatized oil (flavor 231616) 0,3 g
purified water 61,41 g

How to take, the dosage

Outwardly.
The drug consumption per application is on average 0.5 cm of gel on the scar surface of 20-25 cm2. Adults apply the drug 2-3 times a day, children over 1 year old apply the drug 1-2 times a day. The gel is applied as a thin layer and lightly rubbed into the scar tissue. The course of treatment for fresh scars (including ankylosis (contractures) of the joints, traumatic tendon contractures, stretch marks after pregnancy) is on average 4 weeks. In case of long-standing hard scars (including ankylosis (contractures) of joints, traumatic tendon contractures, stretch marks after pregnancy) an occlusive dressing with gel is applied at night.

The course of treatment averages 3-6 months.

In case of Dupuytren’s contracture the course of treatment averages 12 months.

For preventive measures the phase after wound elimination is used (not applied to granulation).

Special Instructions

To enhance the effect of the drug, apply it to previously steamed skin. It may be used in combination with physiotherapeutic measures.

In the treatment of fresh scars it is necessary to avoid ultraviolet irradiation, exposure to cold and intensive massage.

The drug effect during pregnancy, while lactating and in children under 1 year old has not been studied.

Impact on the ability to drive vehicles and mechanisms
Has no effect.

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Contraindications

Hypersensitivity to the components of the drug, pregnancy, breastfeeding, children under 1 year of age.

Side effects

Usually Contraktubex is very well tolerated, even with long-term use.

Most often there were skin reactions at the site of application.

Classification of the frequency of adverse reactions: Very common (> 1/10), common (> 1/100 to< 1/10), infrequent (> 1/1000 to < 1/100), rare (> 1/10000 to < 1/1000), very rare (< 1/10000), frequency not determined (no data on the incidence of adverse reactions currently available).

Skin: frequently: itching, erythema, telangiectasia, scar atrophy; infrequently: skin hyperpigmentation, skin atrophy.

The following spontaneous adverse reactions have also been reported:

Infectious diseases: frequency not determined: pustular rash.
Immune system disorders: frequency not established: hypersensitivity (allergic reactions).
Nervous system disorders: frequency not established: paresthesia.
Skin disorders: frequency not established: urticaria, rash, itching, erythema, skin irritation, papules, burning sensation, feeling of tension, contact dermatitis.

General disorders and disorders at the application site: frequency not established: swelling, pain and peeling at the application site.

Itching, which is a manifestation of natural processes in the formation of the scar, usually does not require discontinuation of the drug.

If any of the side effects specified in the instructions worsen, or any other side effects not specified in the instructions are noted, you should immediately inform the doctor.