Broncholitin, syrup 125 g

Whooping cough, Lung inflammation (pneumonia), Bronchitis, Cough, Chronic obstructive pulmonary disease, Bronchial asthma

Indications

As part of complex therapy for various respiratory diseases accompanied by dry cough, including:
acute inflammatory diseases of the upper respiratory tract;
acute and chronic bronchitis;
tracheobronchitis;
COPD;
bronchial asthma;
pneumonia;
bronchiectasis;
whooping cough

Pharmacological effect

Pharmacotherapeutic group: Combined antitussive agent (antitussive + sympathomimetic agent)

Pharmacological action

Combined drug with antitussive and bronchodilator effects.

Glaucine hydrobromide suppresses the cough center without leading to respiratory depression, constipation or drug dependence.

Ephedrine dilates the bronchi, stimulates breathing and, due to its vasoconstrictor effect, eliminates swelling of the bronchial mucosa.

Basil oil has a slight sedative, antimicrobial and antispasmodic effect.

Pharmacokinetics

Suction

After oral administration, glaucine hydrobromide and ephedrine hydrochloride are quickly and well absorbed from the gastrointestinal tract. Cmax of glaucine is reached after 1.5 hours.

Metabolism and excretion

Glaucine hydrobromide is metabolized in the liver and excreted primarily in the urine.

Ephedrine hydrochloride is excreted unchanged in the urine. T1/2 is 3-6 hours.

Special instructions

Please note that the dosage form contains ethanol.

Impact on the ability to drive vehicles and machinery

Due to the possible occurrence of dizziness and visual impairment, caution should be exercised when performing work that requires increased attention and speed of psychomotor reactions, incl. when driving a car and working with machinery.

Active ingredient

Glaucine, Ephedrine, Basilica oil

Composition

Active substances
ephedrine
glaucine
Excipients: common basil oil – 5.75 mg, citric acid monohydrate – 2.99 mg, sucrose – 2012 mg, methyl parahydroxybenzoate – 6.9 mg, propyl parahydroxybenzoate – 1.15 mg, polysorbate 80 – 57.5 mg, ethanol 96% (1.7 vol.%) – 69 mg, purified water – up to 5 ml.

Pregnancy

Contraindicated for use in the first trimester of pregnancy and during breastfeeding.

During other periods of pregnancy, this remedy should be used with caution.

Contraindications

arterial hypertension;
IHD;
severe organic heart disease;
heart failure;
pheochromocytoma;
thyrotoxicosis;
insomnia;
angle-closure glaucoma;
prostatic hyperplasia with clinical manifestations;
I trimester of pregnancy;
lactation period (breastfeeding);
children under 3 years of age;
hypersensitivity to the components of the drug used.

With caution

Patients with a tendency to develop drug dependence. The dosage form contains ethanol, so caution should be exercised when prescribing the drug in childhood, in patients with liver disease, chronic alcoholism, epilepsy, brain diseases, and in the second and third trimesters of pregnancy.

Side Effects

From the cardiovascular system: tachycardia, extrasystole, increased blood pressure.

From the side of the central nervous system: tremor, agitation, insomnia, dizziness, in children – drowsiness.

From the senses: visual impairment.

From the digestive system: nausea, vomiting, anorexia, constipation.

From the endocrine system: increased libido, dysmenorrhea.

From the urinary system: difficulty urinating, urinary retention in patients with prostatic hyperplasia.

Dermatological reactions: rash, increased sweating.

Other: tachyphylaxis.

Interaction

This remedy can be used simultaneously with antibiotics, antipyretics and vitamins.

Ephedrine weakens the effect of opioid analgesics and hypnotics.

When using ephedrine simultaneously with cardiac glycosides, quinidine, tricyclic antidepressants, the risk of developing arrhythmias increases.

With the simultaneous use of ephedrine with reserpine and MAO inhibitors, a sharp increase in blood pressure is possible.

With simultaneous use of ephedrine with non-selective beta-blockers, the bronchodilator effect may be reduced.

There is no data on drug interactions between glaucine and other drugs.

Manufacturer

Sopharma JSC, Bulgaria