Umkalor

Pharmacotherapeutic group
Antimicrobial agent of plant origin

Pharmacological properties
It has antimicrobial action, mucolytic properties, increases nonspecific resistance.

Pharmacokinetics
Pelargonium sidiformis roots liquid extract contains a large number of
biologically active substances that together determine its pharmacological activity. Therefore, data on the pharmacokinetics of individual chemical components included in the extract are not sufficient for extrapolation to the drug as a whole.

Indications

Tracheitis, sinusitis, colds, Pharyngitis, maxillary sinusitis, cough, flu, bronchitis, runny nose (rhinitis), acute and chronic inflammatory diseases of the respiratory tract and ENT-organs (sinusitis, rhinopharyngitis, tonsillitis, bronchitis) in the treatment.

Composition

100 g of the solution contains:

Active ingredients:
Pelargonium sidiformis root extract liquid EPs 7630 (1 : 8-10) – 80 g,
extractant – ethanol 11% (w/w)

Additional Components:
Glycerol 85% – 20 g

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How to take, the dosage

Adults and children over 12 years are recommended to take orally 20-30 drops 3 times a day;
Children aged 6 to 12 years – 10-20 drops 3 times a day;
Children from 1 to 6 years – 5-10 drops 3 times a day.

The drug should be taken 30 minutes before meals with a small amount of liquid.

When dosing the drug keep the bottle upright and, if necessary, gently tap the bottom of the bottle.

After the disease symptoms have disappeared it is recommended to continue treatment for several days to prevent a relapse. The average duration of treatment course is 10 days.

Interaction

Concomitant use with anticoagulants, including coumarin derivatives, may increase their anticoagulant effect and the occurrence of bleeding (nosebleeds, bleeding gums).

Special Instructions

During storage liquid plant extracts tend to cloud over, but it does not affect their pharmacological effectiveness. Since Umkalor is a natural product, slight changes in color and taste of the drug are possible.
Due to the ethanol content of 12% (vol/vol) in the drug it should be considered that the maximum single dose for children over 12 years and adults contains 0.125 g of absolute ethyl alcohol, the maximum daily dose for children over 12 years and adults contains 0.375 g of absolute ethyl alcohol. A single dose for children under 12 years of age contains less than 0.1 g of absolute ethyl alcohol.
While administering the drug it is necessary to be careful while performing potentially dangerous activities requiring high concentration and quick psychomotor reactions (including driving vehicles and operating moving mechanisms).
In case of absence of therapeutic effect of the drug during 7 days, if the fever persists for several days, if dyspnea or bloody sputum appear, if signs of liver dysfunction (such as yellowing of the skin, yellowing of whites of the eyes), it is necessary to consult a physician.

Synopsis

Transparent or slightly opalescent liquid of light brown to reddish-brown color.

Contraindications

Hypersensitivity to the drug components, susceptibility to bleeding, severe hepatic and renal failure, children under 1 year of age (due to the presence of ethyl alcohol in the drug), concomitant use of anticoagulants.

With caution
Alcoholism, brain injury, brain disease, liver and kidney function disorders (no experience of use), children from 1 year.

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Side effects

Evaluation of the frequency of adverse reactions is based on the WHO classification:

Very frequent – 1/10 appointments (≥10%),
Frequent – 1/100 appointments (≥1% but < 10%),
Infrequent – 1/1000 appointments (≥0.1% but < 1%),
Rare – 1/10000 appointments (≥ 0.01% but < 0.1%),
Very rare – less than 1/10000 appointments (< 0.01%).

Disorders of the immune system, skin and subcutaneous tissue
Rarely, allergic reactions may occur;

Respiratory, thoracic, and mediastinal disease
Rarely, minor nosebleeds may occur;

Gastrointestinal disorders
Infrequent gastrointestinal complaints (such as nausea, vomiting, epigastric pain, or diarrhea), rarely, minor bleeding of the gums;

Hepatobiliary disorders
Signs of liver dysfunction (such as yellowing of the skin, yellowing of the whites of the eyes) may occur. The causal relationship of this manifestation with the drug intake is not confirmed, the frequency of occurrence is unknown.

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Overdose

No cases of drug overdose have been reported so far.
The drug has good tolerability.

Pregnancy use

Due to the lack of sufficient clinical data, it is not recommended to use the drug during pregnancy and breastfeeding.