Binocrit, 5000 me/0.5 ml syringes 6 pcs

Erythropoietin is a glycoprotein that stimulates erythropoiesis, activates mitosis and maturation of erythrocytes from erythrocyte precursor cells.

Indications

anemia in adults and children caused by chronic renal failure, including: anemia due to chronic renal failure in children and adults on hemodialysis, as well as in adults on peritoneal dialysis;

Pharmacological effect

Erythropoietin is a glycoprotein that stimulates erythropoiesis, activates mitosis and maturation of red blood cells from erythrocyte progenitor cells.

Special instructions

When prescribing the drug Binocrit, blood pressure must be checked and strictly controlled in all patients. Epoetin alfa should be used with caution in patients with hypertension if they are not receiving appropriate treatment, if treatment is inadequate, or if the hypertension is poorly controlled.

Active ingredient

Epoetin alfa

Composition

1 ml of solution for intravenous and subcutaneous administration contains:

Active substance:

Epoetin alfa;

Excipients:

sodium dihydrogen phosphate dihydrate,

sodium hydrogen phosphate dihydrate,

sodium chloride,

glycine,

polysorbate 80,

hydrochloric acid,

sodium hydroxide,

water for injections.

Contraindications

hypersensitivity to the active substance and excipients included in the drug;

Side Effects

From the blood and lymphatic system: infrequently – thrombocythemia (in patients with malignant neoplasms); frequency unknown – antibody-mediated PRCA1, thrombocythemia (in patients with chronic renal failure).

Interaction

There is no data on the interaction of epoetin alfa with other drugs.

Overdose

The therapeutic range of the drug is wide.

Storage conditions

At 2–8 °C (do not freeze).

Shelf life

2 years

Manufacturer

IDT Biology GmbH, Germany