Ferretab comp., 30 pcs.

Ferrethab comp. – is a remedy for the treatment and prevention of iron deficiency conditions.

The action is determined by the properties of its constituent active ingredients.

Iron fumarate is a salt of iron, a trace element necessary for the synthesis of hemoglobin. When iron is used in the form of salts it is quickly replenished in the body, which leads to gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, soreness and dry skin) and laboratory symptoms of anemia.

Folic acid is necessary for normal maturation of megaloblasts and formation of normoblasts. It stimulates erythropoiesis, is involved in the synthesis of amino acids, nucleic acids, purines and pyrimidines, choline metabolism. During pregnancy it protects the body from teratogenic factors.

In serum iron is bound to transferrin, is involved in the formation of hemoglobin, myoglobin, cytochrome oxidase, catalase and peroxidase or stored in body tissues as ferritin.

Pharmacokinetics

The excretion of iron occurs with feces, urine and sweat.

Folic acid is absorbed mainly in the upper intestine (duodenum) and is 64% bound to proteins. It is metabolized in the liver and excreted mainly through the kidneys and partially with the feces.

Indications

Treatment and prevention of iron deficiency conditions (pregnancy, disorders of iron absorption in the gastrointestinal tract, prolonged bleeding, unbalanced and incomplete diet).

Active ingredient

Iron fumarate, Folic acid

Composition

Active substance:

(1 capsule contains 3 mini tablets of iron fumarate and 1 mini tablet of folic acid),

iron fumarate 163.56 mg,

folic acid 0.54 mg;

Associates:

Lactose monohydrate, 34.47 mg;

Silica colloidal dioxide, 2.3 mg;

/p>

magnesium stearate – 2.3 mg;

polyacrylate (30% dispersion) – 13.98 mg;

MCC – 24.25 mg.

How to take, the dosage

Ferretab Comp. is taken orally on an empty stomach with plenty of fluids, 1 capsule per day.

In severe deficiency of iron or folic acid it is necessary to increase the dose to 2-3 capsules per day.

The maintenance treatment should be continued for at least 4 weeks after achieving normal hemoglobin levels to normalize serum ferritin, which reflects iron reserves in the body.

Interaction

Co-administration with antacids impairs iron absorption.

Co-administration with antibiotics of tetracycline group should be avoided due to impaired iron absorption.

Cholestyramine, phenytoin, phenobarbital, carbamazepine, sulfasalazine, hormonal contraceptives, folic acid antagonists, trimethoprim, triamterene, solid foods, bread, raw cereals, dairy products, eggs, tea decrease iron absorption.

Special Instructions

Before starting therapy with an iron drug, serum iron levels and serum ferritin should be investigated (i.e., to document iron deficiency).

When taking the drug, dark staining of feces is possible; the benzidine test is false positive.

Contraindications

• Hypersensitivity to components of Ferretab comp.;
• Diseases accompanied by iron accumulation in the body (aplastic and hemolytic anemia, thalassemia, hemosiderosis, hemochromatosis);
• anemia not caused by iron or folic acid deficiency.

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Side effects

It is usually well tolerated.

In some cases there may be temporary adverse effects on the gastrointestinal tract – a feeling of fullness and discomfort in the stomach, nausea, vomiting, allergic reactions, constipation.

Overdose

Symptoms: increased manifestation of side effects.

Treatment: investigation of serum iron and serum ferritin levels.

If serum ferritin levels are significantly higher than normal, an iron chelator (desferal) should be administered according to the manufacturer’s recommended dose.

Pregnancy use

Application is possible in case of indications.