Ascorbic acid, twist, 10 pcs.

Vitamin C (ascorbic acid) is considered the most broad-spectrum antioxidant, fights free radicals and removes them from the body, supports intensive production of antibodies, increases the body’s resistance to various infections, thanks to the resistance of the cells themselves to penetration of pathogenic agents.

Indications

As a dietary food supplement – an additional source of vitamin C and sucrose.

Composition

Ascorbic acid;

How to take, the dosage

Ascorbic acid is taken orally, after meals.
Withpreventive purposes are prescribed:
Adults-50-100 mg/day; children 25 mg/day. During pregnancy and lactation – 300 mg/day for 10-15 days, then 100 mg/day.
Therapeutic purposes are prescribed:
Adults-50-100 mg 3-5 times a day; children 50-100 mg 2-3 times a day. The duration of treatment depends on the nature and course of the disease and is recommended by the doctor.

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Interaction

Pharmaceutically incompatible with aminofillin, bleomycin, cefazolin, cefapirin, chlordiazepoxide, estrogens, dextrans, doxapram, erythromycin, methicillin, nafcillin, benzylpenicillin, warfarin.

Increases the blood concentration of benzylpenicillin and tetracyclines at a dose of 1 g / day increases the bioavailability of ethinylestradiol (including those included in oral contraceptives). Reduces the effectiveness of heparin and indirect anticoagulants.

Concomitant use with acetylsalicylic acid increases urinary excretion of ascorbic acid and decreases excretion of acetylsalicylic acid.

Increases the risk of crystalluria when treated with salicylates and short-acting sulfonamides, slows the renal excretion of acids, increases the excretion of drugs with an alkaline reaction (including alkaloids.alkaloids), reduces the blood concentration of oral contraceptives. Increases the total clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body.

Quinoline drugs, calcium preparations, salicylates, glucocorticosteroids deplete ascorbic acid reserves during long-term use.

In concomitant use reduces the chronotropic effect of isoprenaline.

In prolonged use or use in high doses may prevent the interaction of disulfiram and ethanol.

In high doses increases excretion of mexiletine by the kidneys.

Barbiturates and primidone increase urinary excretion of ascorbic acid.

Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubal reabsorption of amphetamine and tricyclic antidepressants.

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Contraindications

Hypersensitivity to the components of Ascorbic acid.

Do not prescribe high doses in patients with increased blood clotting, thrombophlebitis and tendency to thrombosis, as well as in patients with diabetes and conditions accompanied by high blood sugar.

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Overdose

Symptoms with prolonged use of high doses (more than 1 g) – Headache, increased central nervous system excitability, insomnia, nausea, vomiting, hyperacid gastritis, gastrointestinal mucosal ulceration, heartburn, diarrhea, difficult urination, staining of urine red, hemolysis (in patients with glucose-6-phosphate dehydrogenase deficiency), inhibition of pancreatic insular function (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (from calcium oxalate), renal glomerular damage, moderate pollakiuria (when taking doses over 600 mg/day).

Decreased capillary permeability (deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies is possible).

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