🐾 Onsior tablets 5 mg for dogs from 2.5 kg to 5 kg Elanco, 28 pcs.

Onsior tablets refers to non-steroidal anti-inflammatory drugs.
Robenacoxib, a part of the drug, is a non-steroidal anti-inflammatory drug of coxib group, is a selective specific COX-2 inhibitor and has anti-inflammatory and analgesic effect. COX is present in two forms: COX-1, the constitutive form of the enzyme, performs protective functions, including in the gastrointestinal tract and kidneys; COX-2, the inducible form of the enzyme, is responsible for the production of mediators, including PGEs, that cause pain, inflammation and fever. When administered orally, robustacoxib is rapidly absorbed in the intestine, entering the systemic bloodstream and most organs and tissues; more than 99% of robustacoxib is bound to plasma proteins. Its maximum plasma concentration is observed after 0.5 hours, bioavailability is 49% in cats and 62% in dogs when using tablets with food and 84% without food. Robenacoxib is metabolized in the liver, excreted mainly with bile (about 70% in cats and about 65% in dogs) and partially with urine; half-life of dogs is about 1.2 hours, of cats – 1.7 hours. Onsior™ tablets according to the degree of impact on the body refers to the moderately hazardous substances (3rd class of hazard according to GOST 12.1.007).

Indications

Active ingredient

Composition

How to take, the dosage

Onsior tablets are administered to dogs and cats individually once a day in the doses shown in the table:

Animal type and weight

Dose of active ingredient (mg/tablet) and number of tablets per animal

dose of active ingredient (mg/tablet) and number of tablets per animal/p>

6 mg

5 mg

10 mg

20 mg

40 mg

Cats

2.5 to 6 kg

1 tablet.

6 to 12 kg

2 tabs.

Dogs

2.5 to 5 kg

1 tablet.

5 to 10 kg

1 tablet.

10 to 20 kg

1 tab

20 to 40 kg

1 tablet.

40 to 80 kg

2 tablets.

It is recommended that the drug be given separately from the feed, but if necessary, the drug can be given along with the feed. Tablets should not be crushed or broken.
Onsior tablets are administered to dogs during surgical operations 30 minutes before induction of anesthesia in a dose of 1-2 mg per 1 kg of animal weight; the treatment may be continued for up to 2 days after surgery; in case of locomotor disorders the drug is used for up to 7 days. Onsior tablets for dogs are administered 30 minutes before or after feeding at a dose of 1-2 mg per 1 kg of animal weight. The course of treatment is determined by the attending veterinarian.
As a rule, the duration of treatment is 7 days. If after 10 days the clinical improvement is not achieved, the drug is discontinued.
In case of overdose of the drug in animals with marked sensitivity to the drug components gastrointestinal disorders, liver or kidney failure may be observed.
There are no specific detoxication means, general measures for the drug elimination from the body are used.
No specific action of the drug during the first use and withdrawal.
Onsior tablets should not be used in pregnant and lactating animals, puppies under 3 months of age.
The recommended interval between the drug administration should be avoided as it may cause reduction of therapeutic effectiveness. In case of missed reintroduction the drug should be administered as soon as possible in the prescribed dose.

Special Instructions

Contraindications

Side effects