Zovirax Duo-Active, 5% cream +1% 2 g

Aciclovir is active against Herpes simplex 1 and 2 types, Varicella zoster virus, Epstein-Barr virus and cytomegaloviruses. Thymidine kinase of virus-infected cells actively converts acyclovir into acyclovir mono-, di- and triphosphate through a series of reactions.

The latter interacts with the viral DNA polymerase and is incorporated into the DNA that is synthesized for new viruses. Thus, “defective” viral DNA is formed, which leads to suppression of replication of new generations of viruses.

Hydrocortisone refers to slightly active glucocorticosteroids. When used topically and topically hydrocortisone has therapeutic activity due to its anti-inflammatory, antipruritic, anti-allergic and anti-exudative (due to its vasoconstrictor effect) action.

Due to combination of antiviral action caused by acyclovir and anti-inflammatory action caused by hydrocortisone Zovirax® Duo-Active prevents formation of vesicular rash on the affected skin areas (when used in prodromal period) and reduces healing time of the formed rash elements.

Indications

Recurrent infection of the skin of the lips caused by the herpes virus (Herpes simplex) in adults and children over 12 years of age.

Active ingredient

Composition

The active ingredients:

acyclovir 50 mg;

hydrocortisone 10 mg.

Excipients: liquid paraffin – 56.5 mg, soft white paraffin – 100 mg, isopropyl myristate – 150 mg, sodium lauryl sulfate – 8 mg, cetostearyl alcohol (cetyl alcohol – 60%, stearyl alcohol – 40%) – 67.5 mg, poloxamer 188 – 10 mg, propylene glycol – 200 mg, citric acid monohydrate – 1.4 mg, sodium hydroxide – 0.6 mg q.s. to pH, hydrochloric acid – q.s. to pH, purified water – q.s. to 1000 mg.

How to take, the dosage

Interaction

Special Instructions

Synopsis

Contraindications

Side effects

Overdose

Pregnancy use