Zovirax Duo-Active, 5% cream +1% 2 g
€20.22 €16.85
Aciclovir is active against Herpes simplex 1 and 2 types, Varicella zoster virus, Epstein-Barr virus and cytomegaloviruses. Thymidine kinase of virus-infected cells actively converts acyclovir into acyclovir mono-, di- and triphosphate through a series of reactions.
The latter interacts with the viral DNA polymerase and is incorporated into the DNA that is synthesized for new viruses. Thus, “defective” viral DNA is formed, which leads to suppression of replication of new generations of viruses.
Hydrocortisone refers to slightly active glucocorticosteroids. When used topically and topically hydrocortisone has therapeutic activity due to its anti-inflammatory, antipruritic, anti-allergic and anti-exudative (due to its vasoconstrictor effect) action.
Due to combination of antiviral action caused by acyclovir and anti-inflammatory action caused by hydrocortisone Zovirax® Duo-Active prevents formation of vesicular rash on the affected skin areas (when used in prodromal period) and reduces healing time of the formed rash elements.
Indications
Recurrent infection of the skin of the lips caused by the herpes virus (Herpes simplex) in adults and children over 12 years of age.
Active ingredient
Acyclovir, Hydrocortisone
Composition
The active ingredients:
acyclovir 50 mg;
hydrocortisone 10 mg.
Excipients: liquid paraffin – 56.5 mg, soft white paraffin – 100 mg, isopropyl myristate – 150 mg, sodium lauryl sulfate – 8 mg, cetostearyl alcohol (cetyl alcohol – 60%, stearyl alcohol – 40%) – 67.5 mg, poloxamer 188 – 10 mg, propylene glycol – 200 mg, citric acid monohydrate – 1.4 mg, sodium hydroxide – 0.6 mg q.s. to pH, hydrochloric acid – q.s. to pH, purified water – q.s. to 1000 mg.
How to take, the dosage
Only for external use.
Adults and children over 12 years
The drug should be applied 5 times a day (about every 4 hours), except at night. The preparation is applied by thin layer on the affected and adjacent skin areas.
It is important to start treatment of recurrent infection as soon as possible and the best time is the prodromal period, i.e. the first appearance of unspecific signs of infection (burning, tingling sensation, prickly skin).
Duration of treatment at least five days.
Do not use the preparation for more than five days. If the disease symptoms persist after 5 days of treatment it is necessary to consult a physician. To prevent the deterioration of the condition and prevent the transmission of infection, you should wash your hands before and after applying the drug, do not rub and do not touch the affected areas of the skin with a towel.
Interaction
When used externally, no interaction with other drugs was found.
Special Instructions
In order to achieve the maximum therapeutic effect and prevent the formation of vesicles (blisters) on the skin it is necessary to start using the drug at the first signs of the disease (burning, itching, tingling, tingling sensation).
In severe symptoms of herpes infection of the lips you should consult a doctor.
Only herpes cream can be used for herpes skin lips. It is not recommended to apply the drug to the mucous membranes of the mouth and eyes, as well as to use the cream for genital herpes.
Avoid getting the cream in the eyes.
Do not put dressings or plasters or special anti-herpes masking patches on the application site of the cream. Patients with immunodeficiency states should follow the doctor’s recommendations when treating any infectious diseases. Since these patients are at high risk of developing resistance to acyclovir, they should not use this drug.
The drug contains cetyl alcohol, which may cause local skin reactions such as contact dermatitis, and propylene glycol, which may cause skin irritation.
Effect on the ability to drive vehicles and mechanisms
Zovirax® Duo-Active has no effect on potentially dangerous activities requiring particular attention and quick reactions (driving a car and other vehicles, working with moving mechanisms, operator’s work, etc.).
Synopsis
Cream for external use is homogeneous, white or white with a yellowish tinge.
Contraindications
- High sensitivity to acyclovir, valacyclovir, hydrocortisone and other components of the drug;
- Dermal lesions caused by other viruses, fungal and bacterial skin diseases, as well as parasitic skin infections;
- Dermal tumors, rosacea, vulgaris, vulgaris, vulgaris and hydrocortisoneSkin lesions caused by other viruses, fungal, bacterial skin diseases, and parasitic skin infections;
- Skin tumors, rosacea, acne vulgaris, perioral dermatitis;
- Children under 12 years of age.
.
Side effects
Adverse reactions were local and occurred at the sites where the drug was applied.
Side effects are classified by organ system and frequency. The frequency of adverse effects was defined as follows: very frequently (≥ 1/10), frequently (≥ 1/100 and < 1/10), infrequently (≥ 1/1000 and < 1/100), rarely (≥ 1/10,000 and < 1/1000), and very rarely (≥ 1/100,000 and < 1/10,000).
Allergic reactions:
Very rare – immediate hypersensitivity reactions, including angioedema.
Skin and subcutaneous tissues:
Often – dry, flaky skin;
Infrequent – transient burning, tingling at the sites of application of the drug; itching;
Rarely – redness of the skin; changes in skin pigmentation; allergic dermatitis, more often associated with a reaction to hydrocortisone or excipients.
Local reactions:
Rarely – symptoms of inflammatory reactions (pain, swelling, redness, local increase in tissue temperature).
If any of the above side effects occur, stop taking the drug and consult a physician immediately.
Overdose
In case of accidental ingestion or single use of the entire contents of the package, no adverse effects were observed.
In case of suspected overdose seek medical attention.
Pregnancy use
The use of Zovirax® Duo-Active during pregnancy and during breastfeeding is not recommended, except when prescribed by a physician (if the estimated benefit to the mother exceeds the potential risk to the fetus and child).
Weight | 0.010 kg |
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Shelf life | 2 years |
Conditions of storage | Store at the temperature not more than 25 ° C. Do not store in the refrigerator. Do not freeze. Keep out of reach of children. |
Manufacturer | Glaxo Welcom Operations, United Kingdom |
Medication form | exterior cream |
Brand | Glaxo Welcom Operations |
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