Unityol,. 50 mg/ml 5 ml 10 pcs
€13.41 €11.73
Unithiol is a complexing agent and has a detoxifying effect.
The active sulfhydryl groups of unitiol interacting with thiol poisons (arsenic compounds, heavy metal salts) and forming with them non-toxic, water-soluble compounds, restore functions of the enzyme systems of the body which are affected by the poison.
In diabetic polyneuropathy, it reduces pain syndrome, improves the condition of the peripheral nervous system and normalizes capillary permeability.
Pharmacokinetics
Absorption
In parenteral administration the drug is quickly absorbed into the blood. The maximum level of the drug in the blood (C max ) is reached 15-30 min after the intravenous injection.
The elimination half-life (T 1/2 ) is 1-2 hours. It is excreted by the kidneys, mainly as products of incomplete and complete oxidation, partially unchanged.
Indications
Alcoholism, Polyneuropathy
- intoxication with arsenic, mercury, bismuth, chromium, cardiac glycosides;
- .Hepatocerebral dystrophy (Wilson-Westphal-Conoval disease);
- chronic alcoholism (as part of complex therapy),
- alcoholic delirium.
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Active ingredient
Sodium dimercaptopropane sulfonate
Composition
1 ml of solution for intramuscular and subcutaneous injection contains:
active ingredients:
dimercaptopropanesulfonate sodium monohydrate (unitiol) 50 mg;
auxiliary substances:
dinatrium edetate (trilon B),
sulfuric acid 0.1 M (to pH 3.1-4.5),
d/i water.
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How to take, the dosage
Unityol is used intramuscularly or subcutaneously.
- In intoxication with arsenic – 5-10 ml of the drug (at the rate of 0.005 g/1 kg), in the 1st day – 3-4 times, 2nd day – 2-3 times, in subsequent days – 1-2 times.
- In intoxication with mercury compounds – on the same schedule for 6-7 days. The treatment is carried out until signs of intoxication disappear.
- In case of digitalis intoxication during the first 2 days the drug is injected 5-10 ml of 5% aqueous solution 3-4 times a day, then 1-2 times a day until cardiotoxic effect is cured.
- Hepatocerebral dystrophy – 5-10 ml of 5% solution daily or every other day; treatment course – 25-30 injections; repeated in 3-4 months if necessary.
- In chronic alcoholism 3-5 ml 2-3 times a week.
- For treatment of delirium – once 4-5 ml.
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Interaction
The simultaneous use of Unityol with drugs containing heavy metals and alkalis is not recommended because Unityol decomposes quickly.
Special Instructions
In acute poisoning, additional therapeutic measures (gastric lavage, oxygen therapy, administration of dextrose, etc.) are carried out.
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Contraindications
- high sensitivity to Unityol,
- hepatic insufficiency,
- arterial hypertension.
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Side effects
- nausea,
- dizziness,
- tachycardia,
- pale skin,
- possible allergic reactions.
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Overdose
Symptoms: dyspnea, hyperkinesias, lethargy, lethargy, stunned, short-term seizures (occurs when the recommended therapeutic dose is exceeded by more than 10 times).
Treatment: symptomatic therapy.
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Weight | 0.100 kg |
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Shelf life | 5 years. |
Conditions of storage | Store in a dark place at temperatures from 0 to 25 ° C. Do not freeze. |
Manufacturer | Yerevan CFF, Armenia |
Medication form | solution |
Brand | Yerevan CFF |
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