Tsipromed, eye drops 0.3% 5 ml

Cyprofloxacin is an antimicrobial drug from the group of fluoroquinolones with a broad spectrum of antibacterial action and bactericidal effect.

The spectrum of antibacterial action of ciprofloxacin includes Gram-negative microorganisms: Esherichia coli, Salmonella spp., Shigella spp., Proteus spp. (indole positive and indole negative), Morganella morganii, Citrobacter spp, Klebsiella spp., Enterobacter spp., Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurella multocida, Pseudomonas spp., Gardnerella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamidia spp.

The following Gram-positive microorganisms are also sensitive to ciprofloxacin: Staphylococcus spp., Streptococcus pyogenes, St. agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes. The drug is mildly toxic.

Indications

Infectious and inflammatory diseases of the eye and its appendages caused by microorganisms sensitive to the drug:

Prevention and treatment of infectious complications from injuries to the eye and its appendages and from operations on the eyeball.

Active ingredient

Composition

Ocular drops 0.3% in the form of a clear solution from colorless to pale yellow.

1 ml – ciprofloxacin (in the form of hydrochloride) 3 mg.

Auxiliary substances:

benzalkonium chloride,

sodium edetate,

lactic acid,

How to take, the dosage

Topically. The drug is injected by 1-2 drops into the conjunctival sac. Frequency of the instillations depends on the severity of the inflammatory process.
In acute bacterial conjunctivitis, simple, scaly and ulcerous blepharitis Tsipromed is prescribed from 4 to 8 times a day depending on the disease severity. The course of treatment is from 5 to 14 days.
With keratitis the drug is prescribed 1 drop at least 6 times a day, with positive effect the maximum course of treatment depending on the severity of corneal damage is 2-4 weeks.

With corneal damage by blue pineapple Cypromed is prescribed as often as possible – at least 8-12 times a day by 1 drop. The course of treatment depends on the course of the disease and usually lasts about 2-3 weeks.

In cases of anterior uveitis the drug is instilled 8-12 times a day with 1 drop.

In acute dacryocystitis and canaliculitis Zypromed is prescribed 6-12 times a day, in chronic ones 4-8 times a day with 1 drop.

In case of wounds of the eye and its appendages for the prevention of secondary infection Tsipromed is prescribed for 1-2 weeks at 1 drop 4-8 times a day.

For the prevention of inflammatory diseases after surgical interventions with perforation of the eyeball, Tsipromed is prescribed 4-6 times a day in 1 drop for the entire postoperative period, usually from 5 days to 1 month.

Interaction

Ciprofloxacin is incompatible with drugs with pH=3-4, which are physically and chemically unstable.

Special Instructions

If a patient wears soft contact lenses, he should not use Zipromed because the preservative may deposit in the soft contact lenses and have an adverse effect on the eye tissue.

Please remove all hard contact lenses before applying the medication and do not wear them again until 15 minutes later.

If other ophthalmic medications are used, the interval between injections should be at least 5 minutes.

Immediately after dosing, decreased visual clarity and mental responsiveness can decrease the ability to actively participate in street traffic, operate machinery, or perform unsupported tasks. This is even more so when the drug is used concomitantly with alcohol.

Contraindications

Side effects

A mild burning sensation for 1-2 minutes (immediately after instillation); Itching, soreness, hyperemia of the mucous membrane of the eye, foreign body sensation in the eye, unpleasant taste in the mouth immediately after injection, decreased visual acuity, allergic reactions, edema of the eyelids, photophobia, lacrimation, appearance of white crystalline precipitate in patients with corneal ulcer, keratitis, keratopathy, appearance of stains or corneal infiltration, development of superinfection.

Overdose

There are no specific symptoms if Zypromed is accidentally ingested.

The following symptoms may occur: nausea, vomiting, diarrhea, headache, fainting, anxiety.

Treatment: ensure adequate fluid intake, maintain acidic urine to prevent crystalluria. If necessary, symptomatic therapy is carried out.

Pregnancy use

Zypromed is contraindicated in pregnancy. If it is necessary to use the drug during lactation, breastfeeding should be stopped.

Pediatric use

Contraindication: children under 1 year of age.

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