Trombless, gel 1000 me/g 30 g

Pharmacodynamics

Direct anticoagulant, has anti-inflammatory, antiproliferative, anti-edema and analgesic effect.

Reduces platelet aggregation, binds antithrombin III, preventing the conversion of prothrombin to thrombin. Inhibits thrombin activity.

Reduces hyaluronidase activity, increases blood fibrinolytic properties. Trombless® improves microcirculation and activates tissue exchange, thus accelerating the resorption of hematomas and

clots and finally restores venous patency, clinically it is accompanied by a pronounced analgesic and anti-inflammatory effect.

Pharmacokinetics

A small amount of heparin is absorbed from the surface of the skin into the systemic blood flow.

Maximal concentration of the drug in blood is observed 8 hours after application.

Heparin excretion mainly occurs through the kidneys, the half-life is 12 hours.

Indications

Active ingredient

Composition

How to take, the dosage

Trombless gel is used externally. The gel is 3-10 cm (depending on the area of the affected area) lightly rubbed into the skin 1-3 times a day.

The treatment is applied daily for 4 to 7 days. The course of treatment is determined by the doctor.

In the treatment of hemorrhoidal nodules the instructions for use of Trompless prescribes the application of the drug on a cotton swab which is applied to the affected area.

Interaction

Special Instructions

Contraindications

Side effects

Long-term use of Trompless may cause local reactions in the form of skin hyperemia and allergic reactions.

Overdose

Overdose is unlikely because systemic absorption is minimal.

Pregnancy use

The percutaneous route of administration is considered the safest – the gel acts locally and provides a concentration of the drug at the lesion site.

There is virtually no overall resorptive effect, and the dose can be reduced if necessary.

These points allow the drug to be used in pregnancy with varicose veins.

Similarities