Tolmio 2.5mg/ml +100 mg/ml 1 ml, 10 pcs.
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- Symptomatic treatment of spasticity in adults due to stroke.
- Treatment of painful muscle spasm associated with diseases of the musculoskeletal system (spondylosis, spondyloarthrosis, cervical and lumbar syndromes).
Active ingredient
Lidocaine, Tolperizone
How to take, the dosage
Adults daily 1 ml 2 times a day, intramuscularly or 1 ml once a day intravenously.
Interaction
There are no data on the interaction with drugs that limit the use of the drug.
Although tolperizone has an effect on the CNS, it does not cause sedation and therefore can be used in combination with sedatives, hypnotics and drugs containing ethanol. It does not increase the effect of ethanol on CNS.
It enhances the effect of nonsteroidal anti-inflammatory drugs, so when administered simultaneously the dose of the latter may need to be reduced.
Special Instructions
Effect on the ability to operate vehicles and mechanisms
Caution should be exercised when driving vehicles and engaging in other potentially dangerous activities that require high levels of concentration and rapid psychomotor reactions.
Contraindications
Hypersensitivity to any of the drug components (including lidocaine), severe myasthenia gravis, children under 18 years of age, pregnancy, lactation (due to lack of data).
Side effects
World Health Organization (WHO) recommended frequency of side effects:
very often | ≥1/10 | |
often | ≥1/100 to <1/10 | |
infrequently | ≥1/1000 to <1/100 | |
rarely | from ≥1/10000 to <1/1000 | |
very rarely | <1/10000 | |
frequency is unknown | cannot be estimated from available data. |
Blood and lymphatic system disorders: very rare – anemia, lymphadenopathy.
Disorders of the immune system: rare – hypersensitivity reactions, anaphylactic reactions, very rare – anaphylactic shock.
Metabolic and nutrition disorders: infrequent – anorexia; very rare – polydipsia.
Psychiatric disorders: infrequent – insomnia, sleep disorders, rarely – loss of activity, depression.
Nervous system disorders: infrequent – headache, dizziness, somnolence; rare – attention deficit syndrome, tremor, seizures, loss of sensitivity, sensory disorders, lethargy.
Visual disorders: rare – visual perception disorders.
Hearing organ and labyrinth disorders: rarely – tinnitus, vertigo.
Heart disorders: rare – angina, tachycardia, palpitations; very rare – bradycardia.
vascular disorders: infrequent – arterial hypotension; rare – hot flashes.
Respiratory system, the thorax and mediastinum disorders: rarely – shortness of breath, nasal bleeding, rapid breathing.
Gastrointestinal disorders: infrequent – gastrointestinal discomfort, diarrhea, dry mouth, dyspepsia, nausea; rarely – pain in epigastrium, constipation, flatulence, vomiting.
Liver and biliary tract disorders: rarely – liver function disorders.
Skin and subcutaneous tissue disorders: rare – allergic dermatitis, sweating, skin itching, urticaria, skin rash.
Musculoskeletal and connective tissue disorders: infrequent – muscle weakness, myalgia, pain in extremities; rare – discomfort in extremities; very rare – osteopenia.
Renal and urinary tract disorders: rarely – enuresis, proteinuria.
General disorders and disorders at the injection site: often – redness of the injection site; infrequently – asthenia (weakness), malaise, fatigue; rarely – feeling of intoxication, feeling of heat, irritability, thirst; very rarely – feeling of discomfort in the chest.
Laboratory and instrumental data: rarely – decreased blood pressure, increased concentration of bilirubin, impaired liver function tests, decreased platelet count, increased white blood cell count, very rarely – increased creatinine level.
Overdose
Symptoms: ataxia, tonic and clonic seizures, dyspnea, respiratory arrest.
treatment: symptomatic and supportive therapy is recommended. There is no specific antidote.
Pregnancy use
The drug is contraindicated in pregnancy and during breastfeeding (due to lack of data).
Similarities
Calmirex
Weight | 0.100 kg |
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Shelf life | 18 months. |
Conditions of storage | Protected from light at a temperature of 8 to 15 ° C. |
Manufacturer | Binnopharm, Russia |
Brand | Binnopharm |
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