Tizin Expert, spray 0.05% 10 ml

Pharmacodynamics:

Xylometazoline (imidazole derivative) is an alpha-adrenergic stimulator, narrows the blood vessels of the nasal mucosa, eliminating swelling and hyperemia of the mucosa. Facilitates nasal breathing in rhinitis.

Hyaluronic acid, a part of the drug, has a moisturizing effect when used in nasal medicines due to its ability to keep mucous membranes moist and creates optimal conditions for regenerative processes.
Action usually begins within 5-10 minutes.

Pharmacokinetics:

In local application it is practically not absorbed, plasma concentrations are so low that they cannot be determined by modern analytical methods.

In humans pharmacokinetic studies have not been conducted.

Indications

Active ingredient

Composition

1 ml of the solution contains:

The active ingredient:

xylometazoline hydrochloride 0.5 mg (0.05 %);

the amount of the active ingredient in one dose for 0.05 % is 0.035 mg of xylometazoline hydrochloride;

excipients:

glycerol – 8.5 mg,

sorbitol – 5 mg,

p> sodium dihydrophosphate dihydrate – 4 mg,

sodium chloride – 3 mg,

Sodium phosphate dihydrate – 0.628 mg,

Sodium hyaluronate – 0.2 mg,

Water for injection – up to 1 ml.

How to take, the dosage

Interaction

Special Instructions

Prolonged use (more than 7 days) and overdose of sympathomimetics that have a decongestive effect may lead to reactive hyperemia of the nasal mucosa. This results in difficulty in nasal breathing, which causes the patient to start using the drug repeatedly or even continuously. This can lead to chronic swelling (medicated rhinitis) and eventually even atrophy of the nasal mucosa (ozenema).

In milder cases, to improve the patient’s condition, the sympathomimetic injections in one nostril may be stopped first, and once the complaints have subsided, the injections may be continued in the other nostril to provide at least partial nasal breathing.

The recommended doses should not be exceeded, especially in children and the elderly.

The drug should not be used continuously for more than 7 days.

If the medication has expired or is out of date, do not throw it down the drain or into the street! Place the medication in a bag and put it in the trash. These measures will help protect the environment!

Synopsis

Contraindications

Side effects

Overdose

Pregnancy use

Similarities