Tiloron, 125 mg 10 pcs

Tyloron

Indications

As part of complex therapy for influenza and other acute respiratory viral infections, herpetic infections.

Prevention of influenza and other acute respiratory viral infections.

Pharmacological effect

Pharmacotherapeutic group: Antiviral immunostimulating agent

Pharmacological action

Low molecular weight inducer of endogenous interferon. It is a synthetic compound of the aromatic series, belongs to the class of fluorenones. Stimulates the formation of interferons alpha, beta, gamma, lambda in the body. The main structures that produce interferon in response to the administration of tilorone are intestinal epithelial cells, hepatocytes, T-lymphocytes, and granulocytes. Tiloron has an immunomodulatory and antiviral effect.

Induction of interferon lambda in lung tissue helps to increase antiviral protection of the respiratory tract during influenza and other respiratory viral infections.

Induces the synthesis of interferon in human leukocytes. Stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression, restores the ratio of T-suppressors and T-helpers. Effective against various viral infections, incl. against influenza viruses, other acute respiratory viral infections, hepatitis viruses and herpes viruses. The mechanism of antiviral action is associated with inhibition of the translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed.

Pharmacokinetics

After oral administration, it is quickly absorbed from the gastrointestinal tract. Bioavailability is 60%. Plasma protein binding is about 80%. Tilorone is excreted virtually unchanged through the intestines (70%) and through the kidneys (9%). T1/2 is 48 hours. Tiloron does not undergo biotransformation and does not accumulate in the body.

Special instructions

It is not recommended to use tilorone in doses exceeding the recommended ones in order to avoid possible short-term depletion of immunocompetent cells.

Active ingredient

Tiloron

Composition

Active substance: tilorone

Pregnancy

Contraindicated for use during pregnancy and lactation (breastfeeding). If it is necessary to use it during lactation, the issue of stopping breastfeeding should be decided.

Contraindications

Hypersensitivity to tilorone; pregnancy, lactation (breastfeeding); children’s age – depending on the dosage form.

Side Effects

Possible: allergic reactions, dyspeptic symptoms, short-term chills.

Interaction

Tiloron is compatible with antibiotics and traditional treatments for viral and bacterial diseases.

Manufacturer

Ozon, Russia