Thiolipon, 600 mg 30 pcs

Thioctic acid (alpha-lipoic acid) is an endogenous antioxidant (binds free radicals), in the body is formed during oxidative decarboxylation of alpha-keto acids.

As a coenzyme of mitochondrial multienzyme complexes is involved in the oxidative decarboxylation of pyruvic acid and alpha-keto acids.

It helps to decrease the concentration of glucose in the blood and increase glycogen in the liver, as well as overcoming insulin resistance. By the nature of its biochemical action it is close to the B vitamins.

Participants in the regulation of lipid and carbohydrate metabolism, stimulates cholesterol metabolism and improves liver function.

It has hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic action. It improves the trophism of neurons.

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Indications

Diabetic polyneuropathy; alcoholic polyneuropathy.

Pharmacological effect

Thioctic acid (alpha-lipoic acid) is an endogenous antioxidant (binds free radicals), formed in the body during the oxidative decarboxylation of alpha-keto acids.

As a coenzyme of mitochondrial multienzyme complexes, it participates in the oxidative decarboxylation of pyruvic acid and alpha-keto acids.

Helps reduce blood glucose concentrations and increase glycogen in the liver, as well as overcome insulin resistance. The nature of the biochemical action is close to B vitamins.

Participates in the regulation of lipid and carbohydrate metabolism, stimulates cholesterol metabolism, improves liver function.

It has hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effects. Improves trophism of neurons.

Special instructions

Patients taking Thiolipon should avoid drinking alcohol.

In patients with diabetes mellitus, constant monitoring of blood glucose concentration is necessary, especially at the initial stage of therapy. In some cases, it is necessary to reduce the dose of insulin or oral hypoglycemic drug to avoid the development of hypoglycemia.

During hypoglycemia, the ability to concentrate and react quickly to drive a car or operate machinery may be impaired.

Impact on the ability to drive vehicles and machinery.

The drug does not affect the ability to drive vehicles or operate machinery that requires increased attention.

Active ingredient

Thioctic acid

Composition

1 film-coated tablet contains:

active ingredient:

thioctic acid (lipoic acid) – 600 mg.

kernel excipients:

colloidal silicon dioxide (Aerosil) – 12.3 mg,

microcrystalline cellulose – 41 mg,

hypromellose (hydroxypropyl methylcellulose) – 8.2 mg,

sodium carboxymethyl starch (Primogel) – 28.7 mg,

magnesium stearate – 8.2 mg,

calcium stearate monohydrate – 8.2 mg,

sodium stearyl fumarate – 8.2 mg,

magnesium hydroxylicate (talc) – 24.6 mg,

lactose monohydrate (milk sugar) – 80.6 mg

Pregnancy

Contraindicated during pregnancy.

During treatment, breastfeeding should be stopped (there is not enough experience in these cases).

Contraindications

Hypersensitivity to the components of Thiolipon.
Pregnancy, breastfeeding (there is no sufficient experience in using the drug).
Children under 18 years of age (efficacy and safety of use have not been established).
Lactose intolerance, lactase deficiency, glucose-galactose malabsorption.

With caution

The drug should be prescribed with caution to patients suffering from diabetes mellitus (dosage adjustment of hypoglycemic agents may be required), as well as chronic alcoholism.

Side Effects

Possible dyspepsia, including nausea, vomiting, heartburn.

In some cases, the development of allergic skin reactions (urticaria) is possible.

Anaphylactic shock.

Hypoglycemia may develop (due to improved glucose absorption).

Interaction

Thioctic acid reacts with ionic metal complexes (for example, with cisplatin), therefore, with simultaneous use of the drug Thiolipon, the effect of cisplatin may be reduced.

After taking Thiolipon in the morning, it is recommended to take iron and magnesium supplements, and also consume dairy products (due to their calcium content) in the afternoon or evening.

When used simultaneously, thioctic acid enhances the effect of insulin and oral hypoglycemic agents.

Alcohol (ethanol) reduces the therapeutic activity of thioctic acid.

Storage conditions

In a place protected from light, at a temperature not exceeding 22 °C

Shelf life

3 years

Manufacturer

Biosynthesis, Russia