Blocker of histamine H1-receptors, ethanolamine derivative.
It has a strong antihistamine and antipruritic effect with a rapid onset of action and duration up to 12 hours, prevents vasodilation and smooth muscle contraction induced by histamine.
With anti-allergic effect, reduces vascular and capillary permeability, inhibits exudation and edema formation, reduces itching, has m-cholinoblocking effect.
Indications
Sneezing, Increased lacrimation, Dermatitis, Allergies, Allergic conjunctivitis, Allergic rhinitis, Skin itching, Pollinosis, Urticaria, Dermatosis
- Pollinosis (hay fever, including allergic rhinoconjunctivitis.
- Allergic rhinoconjunctivitis;
- M Urticaria of various origins;
- Pruritus, pruritic dermatoses;
- acute and chronic eczema, contact dermatitis
- drug allergies
- insect bites.
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Active ingredient
Clemastine
Composition
Active ingredient:
Clemastine 1 mg, which is equivalent to 1.34 mg of clemastine hydrofumarate.
Auxiliary Ingredients:
Lactose monohydrate,
povidone (polyvinylpyrrolidone),
Corn starch,
Magnesium stearate, talc.
How to take, the dosage
1 tablet (1 mg) in the morning and in the evening is administered by mouth to adults and children over 12 years of age. In cases that are difficult to treat, the daily dose may be up to 6 tablets (6 mg).
Children aged 6-12 years are prescribed 1/2-1 tablets before breakfast and at night.
Tablets should be taken before meals with water.
Interaction
Tavegil® potentiates the effect of CNS depressant drugs (hypnotics, sedatives, tranquilizers), m-cholinoblockers, and ethanol.
Special Instructions
To prevent distortion of the results of skin scarification tests for allergens, the drug should be canceled 72 hours before allergy testing.
The tablets contain lactose, so the drug is not recommended for patients with rare congenital diseases associated with galactose intolerance, severe lactase deficiency and impaired glucose-galactose absorption.
Use in pediatrics
Tavegil® in tablet form is contraindicated in children under 6 years of age. Tavegil® in the form of solution for intravenous and intravenous injections may be used for treatment of children over 1 year of age.
Effect on driving and operating machinery
Klemastin has a slight sedative effect (mild to moderate in intensity), therefore, patients taking Tavegil® should refrain from driving vehicles, operating machinery and other activities that require increased attention and rapid psychomotor reactions.
Synopsis
Tablets white or almost white, round, flat, with a beveled edge, on one side of the tablet risk and engraved “OT”.
Contraindications
- lower respiratory tract diseases (including. bronchial asthma;
- current use of MAO inhibitors;
- children under 6 years of age;
- pregnancy;
- pregnancy (breastfeeding).pregnancy;
- pregnancy (breastfeeding);
- high sensitivity to the components of the drug.
Caution should be exercised when using Tavegil® in patients with stenotic peptic ulcer, pyloroduodenal obstruction, bladder neck obstruction, and prostatic hypertrophy accompanied by urinary retention, with increased intraocular pressure, hyperthyroidism, diseases of the cardiovascular system (including arterial hypertension, hypertension and hypertension in the arteries).
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Side effects
Definition of the frequency of adverse reactions: very frequently (≥1/10); frequently (≥1/100, < 1/10); infrequently (≥1/1000, < 1/100); rarely (≥1/10 000, < 1/1000); very rarely (< 1/10 000).
Nervous system: frequently – increased fatigability, drowsiness, sedative effect, weakness, feeling of fatigue, lethargy, impaired coordination of movements; infrequently – dizziness; rarely – headache, tremor, stimulant effect.
The digestive system: rare – dyspepsia, nausea, vomiting, gastralgia, very rare – constipation, dry mouth, in some cases – loss of appetite, diarrhea.
The respiratory system: rare – clotting of bronchial secretion and difficult phlegm discharge, a feeling of pressure in the chest and breathing difficulties, stuffy nose.
Cardio-vascular system: rare – decrease in blood pressure (especially in elderly patients), extrasystole, very rare – palpitations.
Sensory system: rare – visual perception impairment, diplopia, acute labyrinthitis, tinnitus.
Urinary system: very rarely – frequent urination, difficulty in urination.
Blood system: rare – hemolytic anemia, thrombocytopenia, agranulocytosis.
Dermatological reactions: rare – skin rash, photosensitization.
Allergic reactions: rare – anaphylactic shock.
Overdose
Symptoms: overdose of antihistamines can lead to both depressing and stimulating effects on the CNS.
Pregnancy use
The use of the drug is contraindicated during pregnancy and breastfeeding.
Similarities
Klemastin, Tavegil
Weight | 0.015 kg |
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Shelf life | 5 years. |
Conditions of storage | Store at temperatures not exceeding 30 ° C. Keep out of reach of children. |
Manufacturer | SmithKlein Beecham S.A., Spain |
Medication form | pills |
Brand | SmithKlein Beecham S.A. |
Other forms…
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