Tabex, 1.5 mg 100 pcs

Clinico-pharmacological group

H-cholinomimetic.

Pharmacological action

Activates nicotinic receptors of autonomic ganglia, reflexively stimulates respiratory center, causes release of adrenaline by chromaffin cells of medullary part of adrenal glands, increases BP.

Limits nicotine dependence (due to the competitive relationship in the area of the same receptors and biochemical substrates with which nicotine interacts in the body).

Causes a change in the taste of smoking (making it unpleasant), reduces the urge to smoke and eases the withdrawal symptoms associated with stopping smoking.

Indications

Smoking cessation

Tabex is used in adults as a means of reducing:

• nicotine dependence (to facilitate smoking cessation.

Active ingredient

Citizine

Composition

Light brown film-coated tablets, round, biconvex.

1 film-coated tablet contains:

The active ingredient:

cytisine 1.5 mg.

Associates:

Lactose monohydrate,

microcrystalline cellulose, <

talc,

magnesium stearate.

Composition of the film coating:

opadrai II brown (hypromellose, lactose monohydrate, titanium dioxide (E171), macrogol 3000, triacetin, iron oxide yellow dye (E172), iron oxide red dye (E172), iron oxide black dye (E172)).

In a blister of 20 tablets.

Package contains 5 blisters.

How to take, the dosage

Dosage and administration

Internal.

The dosing regimen

The drug is given for 3 days, 1 tablet. Six times a day (every 2 hours) with a simultaneous reduction in the number of cigarettes smoked. If there is no effect, the drug should be stopped and a new course should be started after 2-3 months.

Interaction

The drug should not be used at the same time as anti-tuberculosis drugs.

Special Instructions

Principles of Precautions for Taking the Drug

The drug should only be used if the patient has a serious and informed intention to quit smoking.

The patient should be warned that using the drug while continuing to smoke may lead to nicotine intoxication.

Impact on ability to drive vehicles and other mechanisms requiring increased concentration

The use of the drug does not cause changes in the psychophysical state of the patient and does not impair the ability to drive vehicles and operate mechanisms.

Interaction with alcohol

There are no data on interaction with alcohol.

Prescription conditions

The drug is available with a prescription.

Contraindications

The contraindication to the use of Tabex is:

• acute myocardial infarction;
• unstable angina;
• arrhythmias;
late cerebral haemorrhage;
• depth atherosclerosis;
• bleeding from major vessels;
• arterial hypertension;
• pulmonary edema;
• gastric and duodenal ulcer (acute phase);
• but alsoBronchial asthma;
• pregnancy;
• pregnancy (breastfeeding);
• high sensitivity to the drug.

With caution: the drug is prescribed in schizophrenia, adrenal chromaffin tumors, gastroesophageal reflux, in CHD (including chronic heart failure), cerebrovascular disease, hyperthyroidism, peptic ulcer, diabetes, renal and liver failure. In children under 18 years old and in patients older than 65 years old the drug should be used after careful evaluation of the ratio of the expected benefit to potential risk.

Side effects

When using the drug the following may occur:

Digestive system disorders: change in taste and appetite, dry mouth, abdominal pain, nausea, constipation, diarrhea.

CNS disorders: headache, dizziness, insomnia, somnolence, increased irritability.

Cardiovascular system disorders: palpitations, slight increase in BP, tachycardia, chest pain, shortness of breath.

Others: myalgia, weight loss, increased sweating, allergic reactions.

Most side effects go away on their own.

Overdose

Symptoms: nausea, vomiting, dilated pupils, general weakness, tachycardia, seizures, respiratory paralysis.

Treatment: gastric lavage, control heart rate, BP, respiratory function; if necessary – administration of infusion solutions, anticonvulsants, cardiotonic, analeptics and other symptomatic drugs.

Pregnancy use

Tabex is not recommended during pregnancy because of the potential risk of embryotoxic effects if taken uncontrolled.

The drug is not recommended during lactation (breastfeeding).

In children under 18 years of age the drug should be used after careful assessment of the ratio of perceived benefit to potential risk.

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Similarities

Resigar A tablet coated film.ob.1,5 mg, 100 pcs.