Sulfacyl sodium Renewal, eye drops 20% 2 ml 2 pcs

Pharmacodynamics

Antimicrobial bacteriostatic agent, sulfonamide. Mechanism of action is due to competitive antagonism with para-aminobenzoic acid and inhibition of dihydropteroat synthetase, disruption of tetrahydrofolic acid synthesis, required for purines and pyrimidines synthesis.

Active against Gram-positive and Gram-negative cocci, Escherichia coli, Shigella spp, Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp, Actinomyces israelii, Toxoplasma gondii.

Pharmacokinetics

When applied topically, the maximum concentration (Cmax) of sulfonamides in cornea (about 3 mg/ml), anterior chamber humour (about 0.5 mg/ml) and iris (about 0.1 mg/ml) is reached within the first 30 minutes after application. Some amount (less than 0.5 mg/ml) persists in the eyeball tissues for 3-4 hours. Penetration of sulfonamides increases with corneal epithelium damage.

Indications

As part of complex therapy. Conjunctivitis and blepharitis in children and adults, purulent corneal ulcer, prevention and treatment of blenorrhea in newborns, gonorrheal and chlamydial eye diseases in adults.

Active ingredient

Composition

Per 1 ml
Active ingredient:
sulfacetamide – 200 mg
Excipients:
sodium thiosulfate – 1 mg
hydrochloric acid (1 M hydrochloric acid solution) – to pH 8.5
water for injection – to 1 ml

How to take, the dosage

Interaction

Special Instructions

Patients with hypersensitivity to furosemide, thiazide diuretics, sulfonylurea or carbohydrate inhibitors may have hypersensitivity to sulfacetamide. After opening, use within 14 days.

If the patient’s visual acuity is temporarily impaired after using the drug, it is not recommended to drive or engage in activities requiring increased attention and reaction until it is restored.

Contraindications

Hypersensitivity to the ingredients of the drug.

Side effects

Burning, lacrimation, threading, itching in the eyes, transient blurring of vision after injection, allergic reactions.

Overdose

Pregnancy use

Similarities