Streptocide, powder 2 g

Streptocid is a broad-spectrum antibacterial agent. Sulfonamide (streptocid) is one of the first representatives of the chemotherapeutic agents of the sulfonamide group. It has a bacteriostatic effect.

The mechanism of action is due to competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to disruption of dihydrofolic acid and then tetrahydrofolic acid synthesis and, as a result, to disruption of nucleic acid synthesis.

Sulfanilamide is active against Gram-positive and Gram-negative cocci, Escherichia coli, Shigella spp, Vibrio cholerae, Haemophilus influenzae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, and against Chlamydia spp.

Indications

Infected wounds of various etiologies,
burns of the 1st and 2nd degree,
superficial pyoderma,
boils,
carbuncles,
acne vulgaris,
impetigo and other purulent-inflammatory skin diseases.

Pharmacological effect

Streptocide is a broad-spectrum antibacterial agent. Sulfanilamide (streptocide) is one of the first representatives of chemotherapeutic agents of the sulfonamide group. Has a bacteriostatic effect.

The mechanism of action is due to competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to disruption of the synthesis of dihydrofolic and then tetrahydrofolic acid and, as a result, to disruption of the synthesis of nucleic acids.

Sulfanilamide is active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Haemophilus influenzae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, as well as against Chlamydia spp., Actinomyces spp., Toxoplasma gondii.

Active ingredient

Sulfanilamide

Composition

Active ingredient:

sulfonamide

Contraindications

Hypersensitivity,
anemia,
renal/liver failure,
congenital deficiency of glucose-6-phosphate dehydrogenase,
azotemia,
porphyria,
pregnancy,
lactation period.

Side Effects

Skin allergic reactions; rarely – nephrotoxic reactions (most likely in patients with impaired renal function); In isolated cases – hypothyroidism.

Interaction

Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

Overdose

In case of accidental ingestion of the powder, gastric lavage is required.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C.

Shelf life

5 years. Do not use after expiration date.

Manufacturer

Tula pharmaceutical factory, Russia