Spazgan, 500 mg/ml+2 mg/ml+0.02 mg/ml 5 pcs 5 pcs

Spazgan is a combination drug, belongs to the group of aldehydic and antispasmodic agents. The drug consists of: non-narcotic analgesic sodium metamizole (analginum), myotropic antispasmodic agent pitophenone hydrochloride and choline-blocking agent fenpiperinia bromide.

Methamisole is a derivative of pyrosolone. It has analgesic, antipyretic, and mild anti-inflammatory effects.

Pitophenone, like papaverine, has a direct myotropic effect on the smooth muscles of internal organs and causes them to relax.

Phenpiveryinia has an additional relaxing effect on the smooth muscles due to its cholin-blocking action.

The combination of the three components of the drug leads to a mutual strengthening of their pharmacological action.

Indications

Active ingredient

Composition

Active substances:

Sodium metamizole 2.5 g,

Pitophenone hydrochloride 10 mg,

Phenpiperinia bromide 100 µg

How to take, the dosage

In colic patients the drug is administered intravenously 1 ampoule (5 ml) slowly over 5-8 minutes.

Repeated administration is possible after 6-8 hours.

The drug can be given intramuscularly, but it takes 20-30 minutes to take effect.

Interaction

Simultaneous use of Spazgan with other non-narcotic analgesics may lead to a mutual increase in toxic effects.

Tricyclic antidepressants, oral contraceptives, allopurinol impair metabolism of metamizole in the liver and increase its toxicity.

Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effects of metamizole. Concomitant use with cyclosporine reduces the blood levels of the latter. Sedatives and tranquilizers increase the analgesic effect of Spazgan.

If the simultaneous use of the above and other drugs is necessary, the doctor should be consulted.

Special Instructions

In patients suffering from bronchial asthma, taking this drug may provoke a seizure.

Contraindications

Side effects

Overdose

Symptoms: vomiting, decreased blood pressure, drowsiness, confusion, nausea, vomiting, epigastric pain, liver and kidney dysfunction, seizures.

Treatment: Gastric lavage, administration of activated charcoal, symptomatic therapy.

Pregnancy use

Spazgan is contraindicated in pregnant women, nursing mothers and children under 3 months of age.

Similarities