A combined antispasmodic analgesic.
Sodium metamizole, a derivative of pyrazolone, is an analgesic-antipyretic with pronounced analgesic, antipyretic and mild anti-inflammatory action, whose mechanism is associated with inhibition of prostaglandin synthesis.
Pitophenone is a myotropic antispasmodic; it has a direct effect on the smooth muscles of internal organs and causes their relaxation.
Phenpiverinia bromide is a m-cholinoblocker and has an additional antispasmodic effect on the smooth muscles.
Toothache, Colds, Radiculitis, Back pain, Migraine, Biliary dyskinesia, Sciatica, Pain after injuries and operations, Lumbago, Neck pain, Colitis, Acne (vulgaris), Renal colic, GI spasms, Colic, Arthrosis and arthritis, Headache, Gallic Colic
Sodium metamizole, Pitofenone, Phenpiperinia bromide
Sodium metamizole 500 mg,
pitophenone hydrochloride 5 mg,
phenpivery bromide 0.1 mg
How to take, the dosage
Adults are prescribed 1-2 tablets. Spasmalin up to 4 times a day.
The maximum daily dose is not more than 8 tablets.
The dosage for children 6-8 years old is 0.5 tablets, 9-12 years old is 3/4 tablets, 13-15 years old is 1 tablet 2-3 times a day.
Other dosage regimens are possible only after consultation with the doctor.
Simultaneous use of Spasmalin with other non-opioid analgesics may lead to mutually reinforcing effects.
In concomitant use tricyclic antidepressants, oral contraceptives, allopurinol impair the metabolism of sodium metamizole in the liver and increase its toxicity.
When used concomitantly, barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effects of sodium metamizole.
Concomitant use of Spasmalin decreases the plasma concentration of cyclosporine.
When used concomitantly, sedatives and tranquilizers increase the analgesic effect of Spasmalin.
Concomitant use with histamine H1-receptor blockers, butyrophenones, phenothiazines, amantadine and quinidine may increase m-cholinolytic effects of the drugs.
Concomitant use with ethanol may mutually enhance the effects.
In patients suffering from bronchial asthma, taking this drug may provoke a seizure.
- ischemic heart disease;
- adenoma of the prostate;
- severe hepatic and renal insufficiency;
- high sensitivity to the components of the drug.
- Decrease in the number of white blood cells
- Decrease in blood pressure
- disorders of kidney function
- allergic reactions.
Symptoms: vomiting, decreased blood pressure, drowsiness, confusion, nausea, epigastric pain, liver and kidney function disorders, seizures.
Treatment: gastric lavage, administration of activated charcoal; symptomatic therapy if necessary.
Spasmalin is contraindicated in pregnant women, nursing mothers and children in the first three months of life.
Maxigan, Spasmalgon, Bral, Spazgan, Revalgin
|Conditions of storage|
In a light-protected place at a temperature not exceeding 25 °C.
Torrent Pharmaceuticals Ltd, India
Torrent Pharmaceuticals Ltd
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