Sorbifer Douroules, 30 pcs.

Pharmacotherapeutic group: iron drug

ATX code: B03A A07 Pharmacological properties

Pharmacodynamics

Iron is an essential component of the body needed for the formation of hemoglobin and oxidation processes in living tissues. The drug is used to eliminate iron deficiency. Durules technology provides gradual release of active ingredient (iron ions) over a long period of time.

The plastic matrix of Sorbifer Durules tablets is completely inert in digestive juices, but completely disintegrates under the influence of intestinal peristalsis, when the active ingredient is completely released.

Pharmacokinetics

Durules is a technology that provides a gradual release of the active ingredient (iron ions), a uniform intake of the drug. Intake of 100 mg twice a day provides 30% higher iron absorption from Sorbifer Durules in comparison with common iron preparations.

Absorption and bioavailability of iron are high. Iron is absorbed mainly in the duodenum and proximal part of the jejunum. Binding to plasma proteins is 90% and more. It is deposited in the form of ferritin or hemosiderin in hepatocytes and cells of the system of phagocytic macrophages, a minor amount is deposited in the form of myoglobia in muscles. The elimination half-life is 6 hours.

Indications

Active ingredient

Composition

1 tablet contains iron sulfate 320 mg, which is equivalent to Fe2+ 100 mg; ascorbic acid (vit. C) 60 mg.

Associates:

magnesium stearate,

povidone K-25,

polythene powder,

carbomer 934P.

Composition of the shell:

Hypromellose,

MacroGol 6000,

titanium dioxide,

iron oxide yellow,

paraffin hard.

How to take, the dosage

Interaction

Special Instructions

Contraindications

Side effects

Overdose