Sanorin, spray 0.1% 10 ml

Sanorin is a vasoconstrictor.

It induces alpha2-adrenoceptors.

Pharmacodynamics

It causes narrowing of mucosal vessels and reduces swelling, hyperemia, exudation of the mucous membrane of the airways, facilitates nasal breathing.

In long-term use the vasoconstrictor effect gradually decreases, therefore after 5-7 days of treatment it is necessary to take a break for a few days.

Indications

Acute rhinitis, sinusitis, laryngitis, eustachitis, rhinoscopy, hay fever, runny nose, allergic rhinitis.

Pharmacological effect

Sanorin is a vasoconstrictor.

Stimulates alpha2-adrenergic receptors.

Pharmacodynamics

Causes constriction of blood vessels in the mucous membranes and reduces swelling, hyperemia, exudation of the mucous membrane of the respiratory tract, and facilitates nasal breathing.

With prolonged use, the vasoconstrictor effect gradually decreases, and therefore after 5–7 days of treatment you should take a break for several days.

Special instructions

With long-term use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), and therefore it is recommended to take a break for several days after 5-7 days of use in adults and after 3 days of use in children.

Active ingredient

Naphazoline

Composition

1 ml contains:

Active ingredient:

naphazoline nitrate 1 mg;

Excipients:

boric acid,

ethylenediamine,

methyl parahydroxybenzoate,

water.

Contraindications

Hypersensitivity, arterial hypertension, enlarged thyroid gland, tachycardia, severe atherosclerosis, glaucoma, children under 2 years of age (0.1% emulsion, 0.05 and 0.1% solution), up to 15 years (0.1% solution).

Side Effects

Irritation of the mucous membrane, reactive hyperemia;
with long-term use – swelling of the mucous membrane;
nausea, headache, increased blood pressure, tachycardia (with resorptive effects).

Interaction

Concomitant use with MAO inhibitors and for a period of up to 14 days after the end of their use increases the risk of developing severe arterial hypertension (release of deposited catecholamines under the influence of naphazoline).

Slows down the absorption of local anesthetics.

Overdose

Symptoms: hypothermia, bradycardia, hyperhidrosis, drowsiness, coma.

Treatment: symptomatic.

Storage conditions

In a place protected from light, at a temperature of 10–25 °C

Shelf life

4 years. An open bottle of the drug should be used within 4 weeks.

Manufacturer

Saneka Pharmaceuticals a.s., Slovakia