Rutacid, 500 mg 20 pcs.

The rutacid has an antacid effect.

Pharmacodynamics

Hydrotalcite has a layered mesh structure with low aluminum and magnesium content. The release of aluminum and magnesium ions occurs gradually depending on the pH of the gastric juice.

The drug ensures fast and prolonged neutralization of hydrochloric acid while maintaining pH close to normal. It has a protective effect on the gastric mucosa. It reduces the proteolytic activity of pepsin and binds bile acids.

Pharmacokinetics

The release of magnesium and aluminum ions occurs gradually in the stomach, depending on the value of pH. Absorption of the drug occurs in the small intestine.

After oral administration the content of magnesium and aluminum ions in the blood plasma is temporarily increased, but there is no penetration into the nervous and bone tissues (with normal renal function). The absorbed portion is excreted by the kidneys.

Indications

Hyperacidity of gastric juice, heartburn, gastritis, peptic ulcer of the stomach and duodenum, reflux esophagitis.

Pharmacological effect

Rutacid has an antacid effect.

Pharmacodynamics

Hydrotalcite has a layered network structure with a low content of aluminum and magnesium. The release of aluminum and magnesium ions occurs gradually depending on the pH of the gastric juice.

The drug provides rapid and long-lasting neutralization of hydrochloric acid while maintaining the pH close to the normal level. Has a protective effect on the gastric mucosa. Reduces the proteolytic activity of pepsin and binds bile acids.

Pharmacokinetics

The release of magnesium and aluminum ions occurs gradually in the stomach, depending on the pH value. Absorption of the drug occurs in the small intestine.

After oral administration, the content of magnesium and aluminum ions in the blood plasma temporarily increases, but penetration into the nervous and bone tissue does not occur (with normal renal function). The absorbed part is excreted by the kidneys.

Special instructions

The interval between the use of the drug and other medications should be at least 1–2 hours.

It is not recommended to use Rutacid® simultaneously with acid-containing drinks (juices, wine).

The drug Rutacid® does not contain sucrose, so it can be used by patients with diabetes mellitus.

Polyols (mannitol) can cause diarrhea.

Active ingredient

Hydrotalcite

Composition

1 tablet contains:

Active substance:

hydrotalcite 500 mg;

Excipients:

mannitol – 836 mg;

sodium saccharinate – 0.6 mg;

sodium carboxymethyl starch – 12 mg;

talc – 35 mg;

magnesium stearate – 14 mg;

mint flavor – 2.4 mg.

Pregnancy

There is no confirmed data on the undesirable effects of hydrotalcite during pregnancy and breastfeeding.

Contraindications

Hypersensitivity to hydrotalcite; children’s age (up to 6 years).

With caution: chronic renal failure, hypophosphatemia.

Side Effects

Side effects rarely occur when taking the drug. Allergic reactions, diarrhea, and belching are possible.

Interaction

Rutacid® reduces the absorption of tetracycline antibiotics, fluoroquinolones (ciprofloxacin, ofloxacin), coumarins, and iron preparations.

Storage conditions

At a temperature not exceeding 30 °C

Shelf life

5 years

Manufacturer

KRKA dd Novo Mesto, Slovenia