Rhinomaris, spray 0.1% 15 ml

Pharmacotherapeutic group

An anticongestive agent – vasoconstrictor (alpha-adrenomimetic).

ATX CODE: R01AA07

Pharmacokinetics

In topical administration it is practically not absorbed; plasma concentrations are so low that they cannot be determined by modern analytical methods.

Pharmacological properties

Rinomaris is a drug for intranasal use.

Xylometazoline has an alpha-adrenomimetic action: it induces constriction of the blood vessels of the nasal mucosa, thus eliminating nasopharyngeal mucosa edema and hyperemia. Facilitates nasal breathing in rhinitis. In therapeutic concentrations it does not irritate nasal mucosa, does not cause hyperemia. Its effect begins within a few minutes after application and lasts for 12 hours.

The sterilized sea water which is part of Rinomaris helps maintain normal physiologic state of the nasal mucosa, thinning of mucus and normalization of its production in the bocalytic cells of the nasal cavity mucosa.

Micronutrients improve the function of the atrial fibrillation epithelium which helps reduce adverse local reactions such as irritation and/or dryness of the nasopharyngeal mucosa.

Indications

acute respiratory diseases with symptoms of rhinitis (runny nose);

allergic rhinitis (hay fever);

sinusitis;

eustachitis;

otitis media (to reduce swelling of the nasopharyngeal mucosa);

preparing the patient for diagnostic manipulations in the nasal passages.

Pharmacological effect

Pharmacotherapeutic group

Anticongestant – vasoconstrictor (alpha-adrenergic agonist).

ATX CODE: R01AA07

Pharmacokinetics

When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.

Pharmacological properties

Rinomaris is a drug for intranasal use.

Xylometazoline has an alpha-adrenomimetic effect: it causes a constriction of the blood vessels of the nasal mucosa, thus eliminating swelling and hyperemia of the nasopharyngeal mucosa. Facilitates nasal breathing during rhinitis. In therapeutic concentrations it does not irritate the mucous membranes and does not cause hyperemia. The effect occurs a few minutes after application and lasts for 12 hours.

Sterilized sea water, which is part of the drug Rinomaris, helps maintain the normal physiological state of the nasal mucosa, thins mucus and normalizes its production in the goblet cells of the nasal mucosa.

Trace elements improve the function of the ciliated epithelium, which reduces adverse local reactions such as irritation and/or dryness of the nasopharyngeal mucosa.

Special instructions

Before use, it is necessary to clean the nasal passages.

Rinomaris® should not be used for a long time, for example, for chronic rhinitis.

Impact on the ability to drive vehicles and operate machinery

Xylometazoline in doses higher than recommended may affect the ability to operate vehicles or equipment.

Active ingredient

Xylometazoline

Pregnancy

During pregnancy and lactation, the drug should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus; recommended doses should not be exceeded.

Contraindications

Arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, thyrotoxicosis, surgical interventions on the meninges (history), children under 6 years of age (for 0.1% solution), hypersensitivity to the components of the drug.

Side Effects

With frequent and/or prolonged use – irritation and/or dryness of the nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion, swelling of the nasal mucosa.

Palpitations, tachycardia, arrhythmias, increased blood pressure, headache, vomiting, insomnia, blurred vision; with long-term use in high doses – depression.

Overdose

Symptoms: increased side effects.

Treatment: symptomatic therapy.

Storage conditions

The drug should be stored out of the reach of children at a temperature not exceeding 25°C.

Shelf life

3 years. Do not use after the expiration date stated on the package.

Manufacturer

JADRAN-GALENSKI LABORATORY j.s., Croatia