Rhinomaris, 0.05% spray 15 ml

Pharmacotherapeutic group
Antagonist – vasoconstrictor (alpha-adrenomimetic).
ATX code: R01AA07

Pharmacokinetics
Pharmacokinetics
Almost not absorbed by local administration. Plasma concentrations are so low as to be undetectable by modern analytical methods.

Pharmacological properties
Rhinomaris is a drug for intranasal application.

Xylometazoline has alpha-adrenomimetic action: it causes nasal mucosa blood vessels narrowing thus eliminating nasopharyngeal mucosa edema and hyperemia. Facilitates nasal breathing in rhinitis. In therapeutic concentrations it does not irritate nasal mucosa, does not cause hyperemia. The action starts a few minutes after application and lasts for 12 hours.

Sterilized sea water, contained in Rhinomaris, helps maintain normal physiologic condition of nasal mucosa, thinning of mucus and normalization of its production in bocalytic cells of nasal cavity mucosa.

Micronutrients improve the function of the atrial fibrillation epithelium, reducing adverse local reactions such as irritation and/or dryness of the nasopharyngeal mucosa.

Indications

Acute respiratory diseases with rhinitis (runny nose);
allergic rhinitis (pollinosis);
sinusitis;
eustachitis;
middle otitis (to reduce nasopharyngeal mucosa edema);
preparation of patients for diagnostic manipulations in the nasal passages.

Active ingredient

Xylometazoline

Composition

Composition in mg per 1 ml of the drug: 0.05%

The active ingredient

Xylometazoline hydrochloride 0.500

Excipients

Particulate matter/p>

Adriatic Sea water 251,000

Potassium dihydrophosphate 0.502

Purified water up to 1 ml

Special Instructions

The nasal passages should be cleaned before use.
Rinomaris® should not be used for a long time, e.g. in chronic rhinitis.

Effect on the ability to drive and operate machinery
Xylomethasoline in doses exceeding the recommended ones may affect the ability to operate vehicles or equipment.

Contraindications

Arterial hypertension, tachycardia, marked atherosclerosis, glaucoma, atrophic rhinitis, thyrotoxicosis, brain surgery (in anamnesis), children under 2 years of age (for 0.05% solution), hypersensitivity to the drug components.

Precautions
Caution is used in diabetes mellitus, angina pectoris (CHD).

Side effects

In frequent and/or prolonged use – irritation and / or dry nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion, nasal mucosa edema.
palpitations, tachycardia, arrhythmias, increased BP, headache, vomiting, insomnia, visual disturbances; with prolonged use in high doses – depression.

Overdose

Symptoms: worsening of side effects.

Treatment: conducting symptomatic therapy.

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Pregnancy use

During pregnancy and lactation the drug should be used only after careful assessment of the risk-benefit ratio for the mother and fetus, it is not allowed to exceed the recommended doses.

Similarities

Atrivin, Galazolin, Xylen, Snoop, Rinonorm, Xymelin Eco, Rinorus, Rinostop, Rinomaris, Xylometazolin, Tisin Classic, Xymelin Eco Menthol, Asterisk, Xyloct, Cold and Flu, Asterisk for Colds, Quatran xylo