Retinoic ointment 0.1% 15 g

Pharmacotherapeutic group:

Tissue regeneration stimulator.

ATC code: [D10AD04]

Pharmacological action

Isotretinoin is one of the biologically active forms of vitamin A.

It inhibits terminal differentiation of sebocytes and hyperproliferation of epithelium of sebaceous gland exit ducts, normalizes the composition of their secretion and facilitates its evacuation.

This decreases sebum production and reduces the inflammatory reaction around the glands. The ointment has an antiseborrheic, anti-inflammatory and keratolytic effect and enhances the regeneration processes in the skin.

Indications

Acne vulgaris, seborrheic dermatitis, rosacea, perioral dermatitis.

Pharmacological effect

Pharmacotherapeutic group:

tissue regeneration stimulator.

ATX code: [D10AD04]

Pharmacological action

Isotretinoin is one of the biologically active forms of vitamin A.

It inhibits the terminal differentiation of sebocytes and hyperproliferation of the epithelium of the excretory ducts of the sebaceous glands, normalizes the composition of their secretion and facilitates its evacuation.

Due to this, sebum production is reduced and the inflammatory reaction around the glands is reduced. The ointment has an antiseborrheic, anti-inflammatory, keratolytic effect, and enhances regeneration processes in the skin.

Special instructions

It is not recommended to apply the ointment to the skin around the eyes, or in cases of severe acute inflammation.

Do not apply to mucous membranes.

During treatment, you should avoid exposure to the sun; if necessary, use sunscreen; preventive and therapeutic use of ultraviolet rays and visiting a solarium are not recommended.

The drug does not affect the ability to drive a car or perform work that requires increased concentration.

Active ingredient

Isotretinoin

Composition

Active substance:

isotretinoin 0.1 g.

Excipients:

butylated hydroxytoluene – 0.05 g,

butylated hydroxyanisole – 0.025 g,

emulsion wax – 8.0 g,

Vaseline oil – 8.0 g,

glycerol (glycerin) – 10.0 g,

ethanol (ethyl alcohol) 95% –10.0 g,

purified water up to 100 g.

Contraindications

Use with caution in chronic diseases of the liver, kidneys, chronic pancreatitis, cardiac decompensation.

Side Effects

In the second week of treatment, an exacerbation reaction is possible – the appearance of new rashes, itching, redness and peeling of the skin. If the reaction is severe, it is recommended to stop treatment for several days until it subsides.

Interaction

The ointment should not be prescribed to patients receiving other drugs from the retinoid group to reduce the risk of hypervitaminosis A.

Recommendations for use

The ointment is applied in a thin layer to the affected areas of the skin 2 times a day.

Storage conditions

At temperatures from 2 to 8 °C.

Shelf life

2 years.

Manufacturer

Retinoids JSC, Russia