Pyrogenal, 25 mcg 1 ml 10 pcs

Pyrogenal is an immunomodulator of wide spectrum of action, the main of which are activation of reticuloendothelial, hypothalamic-pituitary and fibrinolytic systems. Pyrogenal has adjuvant, desensitizing and anti-inflammatory properties, increases general and specific resistance of the body, influences thermoregulatory centers of hypothalamus.

The drug, by stimulating cells of the phagocytic system, activates phagocytosis, the secretion of oxygen radicals, the synthesis of interleukin-1 (IL-1, IL-2), tumor necrosis factor (TNF _L ), interferon (IFN _L ). Acting on fibroblasts, it inhibits the synthesis of collagen by fibroblasts, accelerates the process of fibrocyte maturation.

Stimulates the activity of hyaluronidase: increases tissue permeability, improves the fibrinolytic properties of blood, restores blood circulation, prevents the formation of new and resolves previously formed tight scars and adhesions, prevents vascular obliteration, stimulates tissue regeneration and epithelization.

Activates the function of the adrenal cortex: anti-inflammatory effect, increases the concentration of hormones in the blood. It stimulates the kinin system.

Indications

The drug is intended for non-specific therapy:

The drug is used for immunoprophylaxis and immunorehabilitation in case of incomplete recovery after acute bacterial and viral diseases.

Active ingredient

Composition

1 ml contains:

Active ingredient:

Bacterial lipopolysaccharide for intramuscular injection 25 µg.

How to take, the dosage

V/m, once a day. Injections are made every other day. If necessary, dilute with 0.9% sodium chloride solution for injection. The drug shall not be stored in the opened ampoule.

The initial single dose is 2.5 mcg. On subsequent days the dose is gradually increased by 2.5-5 micrograms. The maximum single dose is 100 micrograms. A full course of 10 to 30 injections. If necessary, the course of injections is repeated in at least 2-3 months.

When pyrogenal is prescribed for pyrotherapy the drug is injected into the stomach once a day starting with 10-25 micrograms, the dose gradually increases up to 100-150 micrograms. The injections are made every 1 or 2 days as prescribed by the doctor. Combined use of intravenous injections with suppositories is also possible by prescription.

Interaction

The drug is compatible and well combined with all medications used in the treatment of the diseases and conditions mentioned in the indications. It enhances the effectiveness of chemotherapeutic drugs in complex therapy.

Contraindications

Pyrogenal must not be administered:

compensated forms of diseases of the cardiovascular system and diabetes are not contraindications to the use of suppositories.

Pregnancy use

It is contraindicated in pregnancy. Breastfeeding should be stopped during treatment.