Piracetam bufus Reneval, 200 mg/ml 5 ml 10 pcs
€3.88 €3.53
Pharmacotherapeutic group: Nootropic agent
Pharmacological action
Notropic agent. It has a positive effect on metabolic processes and blood circulation of the brain. Increases glucose utilization, improves metabolic processes, improves microcirculation in ischemic areas, and inhibits activated platelet aggregation. It has a protective effect in brain damage caused by hypoxia, intoxication, electroshock. It improves integrative activity of the brain. It has no sedative and psychostimulant effect.
Pharmacokinetics
Indications
Psychiatric treatment of intellectual and mental disorders in the absence of a diagnosed dementia.li>
Symptomatic treatment of intellectual and mental disorders in the absence of an established diagnosis of dementia;
reduction of manifestations of cortical myoclonias in piracetam-sensitive patients, both as monotherapy and as part of complex therapy (a trial course of treatment may be conducted to determine sensitivity to piracetam in a particular case).
Active ingredient
Composition
How to take, the dosage
Intravenously. Intramuscular.
Parenteral administration of piracetam is prescribed when oral forms of the drug cannot be used (unconsciousness, difficulty in swallowing).
Intravenous administration is preferable.
The daily dose is infused intravenously through a catheter at a constant rate over a 24-hour period. The total volume of solution to be infused is based on the clinical indications and the patient’s condition.
The bolus intravenous infusion is given for at least 2 minutes; the daily dose is divided into several infusions (2-4) at regular intervals so that the dose per infusion does not exceed 3 g.
Interaction
The possibility of changes in piracetam pharmacokinetics under the influence of other drugs is low, because 90% of the drug is excreted unchanged by the kidneys.
In concurrent use with thyroid hormones there have been reports of confusion, irritability and sleep disturbance.
Special Instructions
With caution, use in patients with significant impairment of hemostasis, major surgery and severe bleeding; with renal insufficiency.
Continuous monitoring of renal function parameters is recommended.
If sleep disturbances occur, it is recommended that the evening dose of piracetam be stopped and this dose be added to the daytime intake.
Contraindications
With caution:hemostasis disorders; extensive surgical interventions; severe bleeding.
Side effects
Central nervous system and peripheral nervous system: motor disinhibition (1.72%), irritability (1.13%), somnolence (0.96%), depression (0.83%), asthenia (0.23%).
In single cases – headache, insomnia, agitation, impaired balance, ataxia, aggravation of the course of epilepsy, anxiety, hallucinations, confusion.
Cardiovascular system disorders: increase or decrease of blood pressure.
Digestive system disorders: in single cases – nausea, vomiting, diarrhea, abdominal pain (including gastralgia).
Metabolism: weight gain (1.29%).
Skin disorders – dermatitis, itching, rash.
Overdose
There has been a single case of dyspeptic complaints in the form of diarrhea with blood and abdominal pain when an oral dose of 75 g was taken.
This appears to be related to the use of a large total dose of sorbitol, which was previously used in the oral dosage form. No other cases of overdose have been identified.
Treatment: in case of overdose it is recommended to carry out symptomatic therapy, which may include hemodialysis. There is no specific antidote.
The effectiveness of hemodialysis for piracetam is 50-60%.
Pregnancy use
Similarities
Weight | 0.090 kg |
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Shelf life | 5 years. |
Conditions of storage | In the light-protected place at the temperature not more than 25 °C. Keep out of reach of children. |
Manufacturer | Update PFC AO, Russia |
Medication form | solution |
Brand | Update PFC AO |
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