Piperazine, tablets 500 mg 10 pcs

How to take, the dosage

Ingestion. In treatment of ascariasis the drug is prescribed for two consecutive days, 2 times a day 1 hour before or 0.5-1 hours after meals in the following doses:

Adults and children from 15 years – 1.5-2.0 g;

Children aged 3 to 5 years – 0.5 g (daily dose of 1.0 g),

5 to 8 years old – 0.75 g (daily dose of 1.5 g),

8 to 12 years old – 1.0 g (daily dose of 2.0 g),

13 to 15 years old – 1.5 g (daily dose of 3.0 g).

It is possible to use the drug in a single dose of 0.5 g to 4.0 g over one day, depending on age.

The maximum daily dose in adults is 4.0 g.

In case of enterobiasis the preparation is prescribed in the same dose for 5 days in a row (1 to 3 courses of therapy with 7 days’ break between the courses) or for one day in a single dose from 0,5 g to 4,0 g depending on the age. During intervals between cycles an overnight enema is prescribed to mechanically flush out pinworms (4-5 glasses of water for adults, 1-2 glasses for children with the addition of ½ teaspoon of sodium bicarbonate per glass of water).

Interaction

Worsens the severity of extrapyramidal disorders caused by chlorpromazine.

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Special Instructions

Piperazine adipinate treatment does not require a special diet or patient preparation. Laxatives are prescribed only if they are prone to constipation.

During the treatment of enterobiasis a strict hygienic regime is observed.

The treatment can be carried out as an outpatient.

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Contraindications

Organic diseases of the central nervous system. Hypersensitivity. Chronic renal failure, pregnancy and breastfeeding. Children under 3 years of age (for this dosage).

Side effects

Nausea, abdominal pain of spastic nature, headache.

In patients with renal failure – neurotoxic complications (muscle weakness, tremor, euphoria, hallucinations, visual impairment, movement coordination disorders).

Overdose

Symptoms: tremor, muscle weakness.

Treatment: gastric lavage, administration of activated charcoal or other enterosorbents, prescription of saline laxatives. If necessary – oxygenation and transfusion therapy. In case of neurological symptoms, thiamine is administered.

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