Piperazine, tablets 500 mg 10 pcs

Piperazine is an antihelminthic drug, effective for ascariasis and enterobiasis. It has a paralyzing effect on nematodes: by disrupting the function of their neuromuscular system it causes paralysis of the musculature.

The effectiveness of dehelminthization by the drug is 90-95%, and with repeated use it can be about 100%.

Because piperazine does not destroy ascarids, there is no danger of absorption of biological toxic products of their decomposition. It is minimally toxic.

Indications

Infestation with roundworms (ascariasis) and pinworms (enterobiasis).

Pharmacological effect

Piperazine is an anthelmintic drug that is effective against ascariasis and enterobiasis. It has a paralyzing effect on nematodes: by disrupting the function of their neuromuscular system, it causes muscle paralysis.

The severity of deworming with the drug is at the level of 90-95%, and with repeated use it can be about 100%.

Due to the fact that piperazine does not destroy ascaris, there is no danger of absorption of biological toxic products of their breakdown. Low toxic.

Special instructions

Treatment with piperazine adipate does not require a special diet or preparation of patients. Laxatives are prescribed only if you are prone to constipation.

During the treatment of enterobiasis, a strict hygienic regime is observed.

Treatment can be carried out on an outpatient basis.

Active ingredient

Piperazine adipate

Composition

1 tablet contains:

Active substance:

piperazine adipate (piperazine adipate) – 500 mg;

Excipients:

talc,

calcium stearate,

corn starch,

sodium carboxymethyl starch (sodium starch glycolate).

Contraindications

Organic diseases of the central nervous system. Hypersensitivity. Chronic renal failure, pregnancy and breastfeeding. Children under 3 years of age (for this dosage).

Side Effects

Nausea, spastic abdominal pain, headache.

In patients with renal failure – neurotoxic complications (muscle weakness, tremor, euphoria, hallucinations, blurred vision, impaired coordination of movements).

Interaction

Increases the severity of extrapyramidal disorders caused by chlorpromazine.

Overdose

Symptoms: tremor, muscle weakness.

Treatment: gastric lavage, taking activated carbon or other enterosorbents, prescribing saline laxatives. If necessary, oxygen and transfusion therapy. For neurological symptoms, thiamine is administered.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf life

5 years.

Manufacturer

Pharmstandard-Leksredstva, Russia