Piobacteriophage complex liquid, 100 ml

Piobacteriophage liquid complex is a drug with specific selective antibacterial action. Piobacteriophage is active against strains of Streptococcus, Proteus, Staphylococcus, Enterococcus, Occitox, Pseudomonas pneumoniae, Klebsiella pneumoniae and E. coli.

Phiobacteriophage lyses sensitive bacteria due to its ability to attach to their membrane and penetrate the cell. Phage particles multiply in the bacterial cell at the expense of the energy resources of the microorganisms, which leads to their death.

After the death of the bacterial cell, mature phage particles emerge, capable of infecting other susceptible microorganisms.

Phiobacteriophage has no effect on other types of bacteria and does not cause disruption of the natural microflora.

Indications

Treatment and prevention of purulent inflammatory and intestinal diseases caused by staphylococci, enterocococci, streptococci, Pseudomonas, Klebsiella, pathogenic E. coli of different serogroups, Proteus when applied internally, rectally and externally:

Active ingredient

Composition

The solution contains:

Active ingredients:

A mixture of sterile filtrates of phagolysates of staphylococci,

Streptococci,

enterococci,

Proteus,

Klebsiella (pneumoniae and oxytocin),

100 ml of Pseudomonas and Escherichia coli.

How to take, the dosage

Piobacteriophage is intended for local and oral administration as well as for rectal administration.

The treatment of purulent inflammatory processes is recommended by simultaneous local administration and oral administration of Piobacteriophage.

Depending on the localization of the infection, Piobacteriophage is recommended for:

1. Topical application in the form of lotions, irrigations, applications and swabs, moistened solutions. In this case, use the necessary amount of solution, based on the size of the affected area. For abscesses, the solution should be injected into the cavity after removal of pus by puncture (the volume of the solution should be slightly less than the volume of the extracted pus).
2. After administration of necessary amount of bacteriophage a capillary drainage shall be left for subsequent administration of repeated doses of the drug.
3. injection of solution into drained cavity of urinary bladder and renal pelvis through cystostoma or nephrostoma.
4. injection of solution into uterine or vaginal cavity, including tampons soaked in solution.
5. Injection, irrigation and gargling as well as insertion of solution-soaked turundae in otolaryngological practice.
6. Injection into the conjunctival sac in ophthalmological practice.
7. Introduction of moistened turundas into periodontal pockets in dental practice.
8. Injection into the rectum in the form of enemas in gastroenterological practice.

The dose of the drug Piobacteriophage and the duration of therapy is determined by the doctor.

The single dose recommended for children under 6 months of age is 5 ml if administered orally or 10 ml if administered rectally.
Recommended single dose for children aged 6-12 months – 10 ml if administered orally and 20 ml if administered rectally.
Recommended single dose for children aged 1-3 years – 15 ml if administered orally and 30 ml if administered rectally.
Recommended single dose for children aged 3-8 years old – 20 ml if given orally and 40 ml if given rectally.
Recommended single dose for children over 8 years old and adults – 30 ml if given orally and 50 ml if given rectally.

When treating pyo-inflammatory diseases and bowel diseases the appropriate single dose is usually administered three times a day.

If when using bacteriophage locally the wound was previously treated with antiseptic, it is necessary to wash the wound with 0.9% sodium chloride solution before using Piobacteriophage solution.

In children under 6 months of age with enterocolitis and sepsis Piobacteriophage solution is administered in the form of high enemas twice or three times a day. If the child does not develop regurgitation and vomiting the drug can be given orally.

The average duration of therapy is from 5 to 15 days.

As a preventive measure, the drug is given in a single dose twice a day for 5-7 days.

Interaction

The use of the drug is possible in combination with other medicines, including antibiotics.

Special Instructions

The bottle of liquid bacteriophage should be shaken before use. Do not use if cloudy!

Contraindications

Not available.

Side effects

No undesirable effects have been reported with Piobacteriophage.

Overdose

There are no treatment measures for overdose.

Pregnancy use

Piobacteriophage may be prescribed by the attending physician during pregnancy and while breastfeeding.

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