Pantogam active, 300 mg capsules 60 pcs

Pantogam active is a nootropic, anticonvulsant.

Pharmacodynamics

The action of Pantogam activity® is due to the presence in its structure of gamma-amino butyric acid, which directly affects the GABAB receptor-channel complex. Pantogam active® is a racemic mixture of equal amounts of the R-form of hopantenic acid and its S-isomer.

The presence of the isomer improves the transport and interaction of the drug with the GABAA receptor. Pantogam active® has more pronounced nootropic and anticonvulsant activity than the preparations of the first generation of propanthenic acid.

Pantogam active® increases resistance of the brain to hypoxia and toxic substances, stimulates anabolic processes in neurons, combines moderate sedative action with a mild stimulating effect.

It has anti-asthenic and mild anti-anxiety effects. It reduces motor excitability and regulates behavior. It activates mental activity and ability to work. Causes inhibition of pathologically increased bladder reflex and detrusor tone.

Pharmacokinetics

It is rapidly absorbed from the gastrointestinal tract. It penetrates through the HEB. It is not metabolized and eliminated unchanged in 48 hours: about 70% of the administered dose – in the urine, about 30% – in the faeces.

Indications

Active ingredient

Composition

Active ingredient:

raz-hopanthenic acid (D,L-hopanthenic acid);

Auxiliary substances:

Microcrystalline cellulose ;

Magnesium stearate.

How to take, the dosage

Overly, 15-20 minutes after a meal, 2-3 times a day, preferably in the morning and afternoon hours.

The course of treatment is 1-4 months, sometimes up to 6-12 months. After 3-6 months a repeated course of treatment is possible.

Interaction

It prolongs the effect of barbiturates, increases the effects of anticonvulsants, prevents the side effects of phenobarbital, carbamazepine, neuroleptics.

The effect of Pantogam active® is enhanced when combined with glycine and etidronic acid.

Potentiates the effect of local anesthetics (procaine).

Special Instructions

It is recommended that you consult a specialist before use.

Contraindications

Side effects

In rare cases, allergic reactions (rhinitis, conjunctivitis, skin rashes) are possible.

In this case the dose is reduced or the drug is cancelled.

Sleep disturbances or drowsiness or head noise are usually transient symptoms and do not require discontinuation of the drug.

Overdose

Symptoms: intensification of side effects.

Treatment: administration of activated charcoal, gastric lavage, symptomatic therapy.