Pancreatin Reneval 10000,10000 units 20 pcs

Pharmacotherapeutic group: digestive enzyme. ATX code: A09AA02 Pharmacodynamics

Pancreatin is a powder from the pancreas glands of pigs. Pancreatic enzymes contained in pancreatin have proteolytic, amylolytic and lipolytic effect and contribute to the breakdown of proteins, fats and carbohydrates, improve the functional state of the gastrointestinal tract (GIT), thus normalizing digestion.

Pharmacokinetics

Pancreatin 10 000 tablets are covered with acid-resistant coating, which is resistant to the influence of gastric hydrochloric acid and thus protects the pancreatic enzymes contained in the preparation from inactivation. Dissolution of the enteric membrane and release of enzymes occurs at neutral or slightly alkaline pH values. Pancreatic enzymes are not absorbed from the gastrointestinal tract.

Indications

To improve digestion in patients with normal gastrointestinal function in case of dietary irregularities;

insufficiency of external pancreatic secretory function (chronic pancreatitis, cystic fibrosis and others);

chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gallbladder;

conditions following resection or irradiation of the gastrointestinal organs, accompanied by indigestion disorders, flatulence, diarrhea (as part of combined therapy);

Preparation for X-ray and ultrasound examination of the abdominal cavity;

Gastrointestinal disorders of functional character (with acute intestinal infections, irritable bowel syndrome and others).

Active ingredient

Composition

How to take, the dosage

The dose of the drug Pancreatin Reneval 10 000 is set individually depending on the disease and severity of symptoms.

If there are no other indications, adults should take 2-4 tablets of Pancreatin Reneval 10,000 with meals. The drug is taken orally without breaking or chewing the tablet (the efficacy of Pancreatin Reneval 10 000 may be reduced by chewing, and the pancreatic enzymes may irritate the oral mucosa if released) and with plenty of fluid (e.g. a glass of water).

The daily dose of pancreatic enzymes, which is 15000-20000 units of lipase/kg body weight, should not be exceeded.

Intensification of the dose should only be done under medical supervision, based on symptomatic findings (e.g., decrease in steatorrhea and abdominal pain).

The duration of therapy is determined by the physician, and varies from a few days (if indigestion is caused by poor diet) to a few months or even years (if continued replacement therapy is necessary).

In children the dosage is determined by the doctor.

Dose for children and adults with cystic fibrosis

In patients with cystic fibrosis, the dose should be adjusted for severity of symptoms, results of steatorrhea control and maintenance of adequate nutritional status (see “Special Precautions”).

The dose should not exceed 10000 IU of lipase/kg body weight per day.

In children, the dosing regimen and duration of treatment are determined by the physician depending on the severity of digestive disorders and the composition of the diet at the rate of 1000 IU of lipase/kg of child body weight at each meal for children under 4 years old and 500 IU of lipase/kg of child body weight at each meal for children over 4 years old.

If there is no improvement after treatment, or if symptoms worsen, or if new symptoms develop, you should consult a physician.

To use the drug only according to the indication, route of administration, and dosage listed in the directions.

Interaction

Special Instructions

Synopsis

Contraindications

Side effects

Possible side effects are listed below in descending frequency of occurrence: very common (≥ 1/10), common (≥ 1/100 to < 1/10), infrequent (≥ 1/1000 to < 1/100), rare (≥ 1/10000 to < 1/1000), very rare (< 1/10000), frequency not determined (cannot be estimated from available data).

Immune system disorders

Very rare: immediate-type allergic reactions (such as skin rash, urticaria, sneezing, lacrimation, bronchospasm, dyspnea), GI hypersensitivity.

Gastrointestinal tract disorders

Very rare: diarrhea, abdominal discomfort, abdominal pain, nausea, vomiting; formation of strictures in the ileocecal and ascending colon in patients with cystic fibrosis when high-dose pancreatin is used.

Urogenital system disorders

Frequency unknown:hyperuricosuria (see section “Special Precautions”).

If you experience or worsen the side effects listed in the instructions, or if you notice any dother side effects not listed in the instructions, tell your doctor.

Overdose

Pregnancy use

Similarities