Omaron, tablets 60 pcs

OMARON is a combined drug with antihypoxic, nootropic and vasodilator effects.

Piracetam activates metabolic processes in the brain by enhancing energy and protein metabolism, accelerating glucose utilization by cells and increasing their resistance to hypoxia, improves inter-neuronal transmission in the CNS, improves regional blood flow in the ischemic area.

Cinnarizine is a selective blocker of slow calcium channels, it inhibits entry of calcium ions into cells and reduces their content in the plasma membrane depot, reduces the tone of arteriolar smooth muscle, reduces

their response to biogenic vasoconstrictors (epinephrine, norepinephrine, dopamine, angiotensin, vasopressin).

It has a vasodilator effect (especially in relation to cerebral vessels, increasing the antihypoxic effect of piracetam) without having a significant effect on BP.

It has moderate antihistamine activity, reduces the excitability of the vestibular apparatus, reduces the tone of the sympathetic nervous system.

Enhances elasticity of erythrocyte membranes and their ability to deform, reduces blood viscosity.

Indications

Active ingredient

Composition

Active substances:

Piracetam 400 mg;

Cinnarizine 25 mg;

Supplementary substances:

Lactose monohydrate 23.5 mg;

Magnesium hydroxycarbonate pentahydrate 46.8 mg;

Povidone (collidon 30) 3.9 mg;

Colloidal silicon dioxide (aerosil A-380) 5.2 mg,

Calcium stearate monohydrate 5.2 mg;

Crospovidone (collidon SL-M) 10.4 mg.

How to take, the dosage

Interaction

In concomitant use of Omaron® the sedative effect of CNS depressants, as well as nootropics, antihypertensives and ethanol may be enhanced.

Vasodilators increase the effect of the drug.

Omaron® improves the tolerability of antipsychotic drugs and tricyclic antidepressants.

Special Instructions

Central and peripheral nervous system disorders: motor disinhibition, irritability, somnolence, depression, asthenia, headache.

In single cases dizziness, ataxia, worsening of epilepsy, extrapyramidal disorders, tremor, unsteadiness, decreased ability to concentrate, insomnia, agitation, anxiety, hallucinations, increased sexuality have been reported.

Cardiovascular system: decreased or increased blood pressure.

Digestive system disorders: dyspeptic phenomena, feeling of dry mouth; in single cases – nausea, vomiting, diarrhea, abdominal pain, cholestatic jaundice.

Skin disorders: dermatitis, itching, skin rash in single cases.

Metabolism: weight gain.

Allergic reactions: angioedema.

Others: increased sweating; in single cases – lupus-like syndrome, lichen planus.

Synopsis

Features

Contraindications

Side effects

Central and peripheral nervous system disorders: motor disinhibition, irritability, somnolence, depression, asthenia, headache.

In single cases dizziness, ataxia, worsening of epilepsy, extrapyramidal disorders, tremor, unsteadiness, decreased ability to concentrate, insomnia, agitation, anxiety, hallucinations, increased sexuality have been reported.

Cardiovascular system: decreased or increased blood pressure.

Digestive system disorders: dyspeptic phenomena, feeling of dry mouth; in single cases – nausea, vomiting, diarrhea, abdominal pain, cholestatic jaundice.

Skin disorders: dermatitis, itching, skin rash in single cases.

Metabolism: weight gain.

Allergic reactions: angioedema.

Others: increased sweating; in single cases – lupus-like syndrome, lichen planus.

Overdose

Symptoms of overdose mainly due to the m-cholin-blocking activity of cinnarizine include: impaired consciousness, vomiting, extrapyramidal symptoms, decreased blood pressure.

After oral administration of piracetam at a dose of 75 g, diarrhea with blood and abdominal pain were observed.

Treatment: there is no specific antidote.

In case of overdose gastric lavage and administration of activated charcoal, symptomatic and supportive therapy are necessary.

The effectiveness of hemodialysis for piracetam is 50-60%.

Pregnancy use

The drug is contraindicated in pregnancy and lactation.

Similarities