Odeston, tablets 200 mg 50 pcs

A choleretic drug. Increases formation and excretion of bile. It has a selective antispasmodic effect on bile ducts and Oddi sphincter. The drug does not decrease gastrointestinal peristalsis and BP.

Limits bile stasis, prevents cholesterol crystallization and thus development of cholithiasis.

Pharmacokinetics

absorption and distribution

After oral administration, it is rapidly absorbed from the gastrointestinal tract. Cmax in blood after oral administration is reached after 2-3 hours. Weakly bound to plasma proteins.

Elimation

T1/2 is about 1 h. It is excreted in the urine: about 93% – as glucuronate, 1.4% – as sulfonate, 0.3% – unchanged.

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Indications

Biliary dyskinesia, Appetite disorders, cholecystitis, Nausea, Constipation, cholelithiasis

• Biliary dyskinesia and sphincter of Oddi type of hyperkinetic;
• Bile duct dyskinesia and sphincterChronic cholecystitis, cholangitis, cholelithiasis;
• Condition after surgical interventions on gallbladder and biliary tracts;
• drowsing of appetite, nausea, constipation, vomiting (due to bile hyposecretion).

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Active ingredient

Hymecromone

Composition

1 tablet contains:

Active substances:hymecromone 200 mg

Associates: potato starch – 45 mg, gelatin – 3 mg, sodium lauryl sulfate – 1 mg, magnesium stearate – 1 mg.

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How to take, the dosage

The drug is used orally 30 min before meals.

Adults are prescribed 200-400 mg 3 times a day. The daily dose is 1200 mg. The course of treatment is 2 weeks.

If a dose is missed, take the drug as soon as possible. If the time of the next dose is approaching, do not take the missed dose. Do not take a double dose of the drug to make up for a missed dose.

Interaction

Concomitant use of morphine, which causes spasm of the Oddi sphincter, weakens the effect of Odeston.

When using Odeston concomitantly with metoclopramide there is a mutual weakening of action.

Odeston increases the effects of indirect anticoagulants.

Special Instructions

Special Precautions for Disposing of Unused Medication

Do not throw medications down the drain or into household waste containers. You should ask your pharmacist about how to dispose of unused medication. These measures will help protect the environment.

Impact on the ability to drive and operate machinery

The drug does not affect the ability to drive vehicles and to engage in other potentially dangerous activities requiring increased concentration and quick psychomotor reactions.

Contraindications

• Hypersensitivity;
• biliary tract obstruction;
• renal/liver failure;
• HypaticUlcerative colitis, Crohn’s disease;
• Gastric and duodenal ulcer;
• hemophilia;
• children under 18 years of age.

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Side effects

Digestive system: diarrhea, flatulence, abdominal pain, gastrointestinal mucosa ulceration.

Others: allergic reactions, headache.

Overdose

No cases of overdose of Odeston have been reported at this time.

Similarities

Hymecromone