Odeston, tablets 200 mg 100 pcs

Pharmacological group: Drug with choleretic and antispasmodic action

Pharmacotherapeutic group: Biliuretic

Pharmacological action

The diuretic drug. Increases the formation and excretion of bile. It has a selective antispasmodic effect on the bile ducts and sphincter of Oddi. The drug does not decrease gastrointestinal peristalsis and BP.

Limits bile stasis, prevents cholesterol crystallization and thus development of cholithiasis.

Pharmacokinetics

absorption and distribution

After oral administration, it is rapidly absorbed from the gastrointestinal tract. Cmax in blood after oral administration is reached after 2-3 hours. Weakly bound to plasma proteins.

Elimation

The T1/2 is about 1 hour. It is excreted in the urine: about 93% – as glucuronate, 1.4% – as sulfonate, 0.3% – unchanged.

Indications

Biliary dyskinesia, cholecystitis, appetite disorders, nausea, cholelithiasis, constipation, biliary colic – Biliary dyskinesia and sphincter of Oddi type (hyperkinetic);
– Biliary dyskinesia and sphincter of Oddi type. – Chronic cholecystitis, cholangitis, cholelithiasis;
– conditions after surgical interventions on the gallbladder and biliary tracts;
– decreased appetite, nausea, constipation, vomiting (due to bile hyposecretion).

Active ingredient

Hymecromone

Composition

The tablets are white to white with a yellowish tint, round, flat cylindrical, beveled and engraved on one side with the letters “Ch”.

1 tablet:

Himecromone 200 mg

Associates: potato starch – 45 mg, gelatin – 3 mg, sodium lauryl sulfate – 1 mg, magnesium stearate – 1 mg.

How to take, the dosage

The drug is used orally 30 min before meals.

Adults are prescribed 200-400 mg 3 times a day. The daily dose is 1200 mg. The course of treatment is 2 weeks.

If a dose is missed, take the drug as soon as possible. If the time of the next dose is approaching, do not take the missed dose. Do not take a double dose of the drug to make up for a missed dose.

Interaction

Concomitant use of morphine, which causes spasm of the sphincter of Oddi, weakens the effect of Odeston.

When using Odeston concomitantly with metoclopramide there is a mutual weakening of action.

Odeston increases the effects of indirect anticoagulants.

Special Instructions

Special Precautions for Disposing of Unused Medicines
Medicines should not be thrown down the drain or into household waste containers. You should ask your pharmacist about how to dispose of unused medication. These measures will help to protect the environment.

Effect on the ability to drive vehicles and operate machinery

The drug does not affect the ability to drive vehicles and engage in other potentially dangerous activities requiring increased concentration and rapid psychomotor reactions.

Contraindications

– Biliary obstruction;
– Renal failure;
– Liver failure;
– Ulcerative colitis;
– Crohn’s disease;
– Gastric and duodenal ulcer;
– Haemophilia;
– Child and adolescent age under 18;
– Hypersensitivity to the components of the preparation.
.

Side effects

Digestive system: diarrhea, flatulence, abdominal pain, gastrointestinal mucosal ulceration.

Others: allergic reactions, headache.

Overdose

No cases of overdose of Odeston have been reported at this time.

Similarities

Hymecromone