Nystatin, vaginal suppositories 250000 units 10 pcs

Pharmacotherapeutic group

Antifungal agent

AtCode

G01AA

Pharmacodynamics:

The polyene antifungal antibiotic is highly active against yeast-like fungi of the genus Candida. In the structure of the antibiotic there are double bonds with high tropicity to the sterol structures of the cell membrane of fungi, which promotes incorporation of the drug molecule into the cell membrane and formation of a large number of channels through which uncontrolled transport of electrolytes occurs; increase of osmolarity inside the cell leads to its death. Resistance develops very slowly.

Pharmacokinetics: When used topically, the drug is practically not absorbed through the mucous membranes.

Indications

Active ingredient

Composition

Active ingredients:

Nystatin – 55.5 mg (250,000 IU)

Excipients:

propyl parahydroxybenzoate (nipazole) – 2.0 mg,

citric acid monohydrate – 0.075 mg,

The suppository base: Solid fat – sufficient amount to obtain a suppository weight of 2.4 g

How to take, the dosage

Interaction

Special Instructions

Treatment should not be interrupted during menstruation.

In case of vaginal fungal diseases, it is recommended to treat the sexual partner at the same time. During treatment it is recommended to avoid sexual intercourse.

Contraindications

Side effects

Local hypersensitivity reactions are possible.

Possible risk of spreading resistant forms of fungi, which requires withdrawal of the drug.

Pregnancy use