Normokinesin, tablets 25 mg 112 pcs

A synthetic benzoquinolysine derivative, it has a specific effect on the CNS similar to reserpine, but unlike the latter, tetrabenazine has little peripheral activity and shorter duration of action.
Tetrabenazine disrupts the metabolism of biogenic amines such as serotonin and noradrenaline in the brain.

Indications

Hyperkinetic movement disorders in Huntington’s chorea.

Pharmacological effect

A synthetic derivative of benzoquinolysine, it has a specific effect on the central nervous system similar to reserpine, but unlike the latter, tetrabenazine has insignificant peripheral activity and a shorter duration of action.
Tetrabenazine interferes with the metabolism of biogenic amines, such as serotonin and norepinephrine, in the brain.

Special instructions

Tetrabenazine should not be taken in patients with rare hereditary diseases – galactose intolerance, lactase deficiency or glucose-galactose malabsorption.

Active ingredient

Tetrabenazine

Composition

1 tab.:

Contraindications

Hypersensitivity to tetrabenazine or other components of the drug; simultaneous use with reserpine; simultaneous use of MAO inhibitors; presence of hypokinetic/rigid syndrome (parkinsonism); depression; pregnancy and breastfeeding; pheochromocytoma; prolactin-dependent tumors such as pituitary tumors or breast cancer; children under 18 years of age (due to the lack of proven effectiveness and safety of use).
With caution: impaired liver function; renal dysfunction.

Side Effects

Determination of the frequency of adverse reactions: very often (≥1/10), often (≥1/100 to <1/10), infrequently (≥1/1000 to <1/100), rarely (≥1/10,000 to <1/1000), very rarely (<1/10,000), frequency not established (currently there are no data on the prevalence of adverse reactions).

Interaction

Tetrabenazine should not be used simultaneously with reserpine, because it may block the action of reserpine.
Tetrabenazine should not be used concomitantly with MAO inhibitors.

Manufacturer

Trommsdorff GmbH and Co.KG, Germany