Normokinesin, tablets 25 mg 112 pcs

Name: Normokinesin, tablets 25 mg 112 pcs
SKU: 309247
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EAN: 9007653000082 SKU: 309247 Categories: Medicine, Neurology and Psychiatry, Stimulants

Description

A synthetic benzoquinolysine derivative, it has a specific effect on the CNS similar to reserpine, but unlike the latter, tetrabenazine has little peripheral activity and shorter duration of action.
Tetrabenazine disrupts the metabolism of biogenic amines such as serotonin and noradrenaline in the brain.

Indications

Hyperkinetic motor disorders in Huntington’s chorea.

Active ingredient

Tetrabenazine

How to take, the dosage

It is administered orally. Treatment should be carried out under the supervision of a physician experienced in the treatment of hyperkinetic disorders.

The recommended initial dose in Huntington’s chorea for adults is 12.5 mg 1 to 3 times daily. Thereafter, the dose may be increased once every 3 to 4 days by 12.5 mg until optimal therapeutic effect is achieved or until side effects (sedation, parkinsonism, depression) appear.

Interaction

Tetrabenazine should not be used concomitantly with reserpine because it may block the effects of reserpine.

Tetrabenazine should not be used concomitantly with MAO inhibitors.

Special Instructions

Tetrabenazine should not be taken in patients with rare hereditary diseases – galactose intolerance, lactase deficiency or glucose-galactose malabsorption.

Contraindications

Hypersensitivity to tetrabenazine or other drug components; simultaneous use with reserpine; simultaneous use of MAO inhibitors; presence of hypokinetic/rigid syndrome (parkinsonism); depression; pregnancy and breastfeeding period; pheochromocytoma; prolactin-dependent tumors such as pituitary tumors or breast cancer; childhood age under 18 years (due to lack of proven effectiveness and safety of use).
With caution: impaired liver function; impaired renal function.

Side effects

Definition of the incidence of adverse reactions: very common (≥1/10), common (≥1/100 to < 1/10), infrequent (≥1/1000 to < 1/100), rare (≥1/10 000 to < 1/1000), very rare (< 1/10 000), frequency not determined (currently no data on the incidence of adverse reactions are available)

Additional information