Nitroxoline, 50 mg 50 pcs.
€7.91 €6.92
An antimicrobial agent derived from 8-oxyquinoline. The mechanism of action is associated with selective inhibition of bacterial DNA synthesis.
Nitroxoline is active against Gram-positive bacteria: Staphylococcus spp. (including Staphylococcus aureus), Streptococcus spp. beta-haemolytic streptococci, Streptococcus pneumoniae, Enterococcus faecalis), Corynebacterium diphtheriae, Bacillus subtilis; Gram-negative bacteria: Neisseria gonorrhoeae, Escherichia coli, Proteus spp, Klebsiella spp., Salmonella spp., Shigella spp., Enterobacter spp.
Nitroxoline is also active against Mycobacterium tuberculosis, Trichomonas vaginalis, some types of fungi (Candida spp., dermatophytes, molds, some deep mycosis agents).
Indications
Infectious and inflammatory diseases of the urinary tract caused by sensitive microorganisms (including pyelonephritis, cystitis, urethritis), epididymitis;
infected adenoma or carcinoma of the prostate gland, etc.);
prevention of infectious complications during diagnostic and therapeutic interventions (catheterization, cystoscopy, after surgery on the kidneys and urinary tract).
Pharmacological effect
Antimicrobial agent, derivative of 8-hydroxyquinoline. The mechanism of action is associated with selective inhibition of bacterial DNA synthesis.
Nitroxoline is active against gram-positive bacteria: Staphylococcus spp. (including Staphylococcus aureus), Streptococcus spp. (including beta-hemolytic streptococci, Streptococcus pneumoniae, Enterococcus faecalis), Corynebacterium diphtheriae, Bacillus subtilis; gram-negative bacteria: Neisseria gonorrhoeae, Escherichia coli, Proteus spp., Klebsiella spp., Salmonella spp., Shigella spp., Enterobacter spp.
Nitroxoline is also active against Mycobacterium tuberculosis, Trichomonas vaginalis, some types of fungi (Candida spp., dermatophytes, molds, some pathogens of deep mycoses).
Special instructions
During treatment, the urine turns saffron yellow.
Active ingredient
Nitroxoline
Composition
Active ingredient:
nitroxoline 50 mg;
Excipients:
potato starch,
lactose monohydrate,
calcium stearate,
talc,
Aerosil,
sugar,
magnesium carbonate,
povidone,
titanium dioxide,
tartrazine,
Ponceau 4 R,
beeswax,
Vaseline oil
Contraindications
Hypersensitivity (including to other 8-hydroxyquinoline derivatives), renal dysfunction, accompanied by oliguria, anuria; severe liver diseases, cataracts, neuritis, polyneuritis, glucose-6-phosphate dehydrogenase deficiency, pregnancy, breastfeeding.
Side Effects
Dyspepsia (nausea, vomiting), loss of appetite, allergic reactions (skin rash); tachycardia, ataxia, headache, paresthesia, polyneuropathy, liver dysfunction.
Interaction
When Nitroxoline is used together with drugs of the tetracycline group, a summation of the effects of each drug is observed, with nystatin and levorin – a potentiation of the effect.
To avoid the summation of the negative neurotropic effect, Nitroxoline should not be combined with nitrofurans.
Storage conditions
In a dry place, protected from light.
Shelf life
4 years
Manufacturer
Biosynthesis, Russia
Shelf life | 4 years |
---|---|
Conditions of storage | In a dry, light-protected place. |
Manufacturer | Biosintez, Russia |
Medication form | pills |
Brand | Biosintez |
Other forms…
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