Neovir 250 mg/2 ml 2 ml, 3 pcs.

Neovir is an immunomodulatory, antiviral.

Induces formation in the body of high titers of endogenous interferons, especially interferon alpha.

Pharmacodynamics

It has antiviral (against DNA- and RNA-genomic viruses) and pronounced antichlamydial action. Activates bone marrow stem cells, T-lymphocytes and macrophages. It normalizes the balance between subpopulations of T-helper and T-suppressor cells.

In HIV-infection it has an immunomodulatory effect: increases the absorptive activity of serum, increases the ability of leukocytes to synthesize interferon alpha, stimulates the formation of reactive oxygen species by phagocytes.

The peak of interferon activity in blood and tissues is observed several hours after I/m injection and lasts for 16-20 hours. Injection of 250 mg of Neovirinum per month is equivalent to 6-9 million IU of recombinant interferon alfa by dynamics of serum interferon titer.

Pharmacokinetics

T1/2 – 1 h, excreted unchanged in the urine.

Indications

Cytomegalovirus infection, Hepatitis, Prostatitis, HIV infection, Urethritis, Cancer, Flu, Chlamydia, Inflammation of the female genitalia, Herpes

Prevention and treatment of influenza and other acute respiratory diseases of viral etiology (including immunodeficiency.

Infections caused by viruses Herpes simplex, Herpes simplex genitalis, Herpes Varicella zoster (incl. people with immune system disorders);

– CMV infection with a background of immunodeficiency;

– radiation immunodeficiency;

– immunodeficiency states, including HIV infection;

– encephalitis and encephalomyelitis of viral etiology;

– acute and chronic hepatitis B and C;

– urethritis, epididymitis, prostatitis, cervicitis, and salpingitis of chlamydial etiology;

– venereal lymphogranuloma;

– Oncological diseases (combined therapy);

– Multiple sclerosis;

– Candida lesions of the skin and mucous membranes.

Active ingredient

Sodium oxodihydroacridinyl acetate

Composition

1 ml – sodium oxodihydroacridinyl acetate 125 mg.

The excipients:

Sodium citrate 2.5 mg,

citric acid monohydrate 0.5-1.5 mg (to pH 7.5-8.3),

water d/i to 1 ml.

How to take, the dosage

The solution for injection is given by injection/m and the single dose is 250 mg (1 ampoule) or 4-6 mg/kg body weight. If necessary, the single dose of Neovir can be increased to 500 mg.

The course of treatment, if there are no special indications, consists of 5-7 single-dose intravenous injections with an interval of 48 hours. The course dose depends on the clinical picture. Course duration is 8-12 days. When prolonged and prophylactic use the interval between injections of Neovir is 3-7 days.

In case of HIV infection the solution for injection is used as part of combination therapy. A course of treatment consists of 10 intravenous injections of 250 mg with an interval of 48 hours between injections. After the course of therapy, there is a break of 2 months. The number of repeated courses is not limited.

Interaction

In the course of clinical trials and use of the drug in clinical practice there have been no cases of incompatibility or potentiation of the drug in interaction with other medicinal products.

There is no information about physicochemical incompatibility of Neovir with other medicinal products.

Special Instructions

In case of poor tolerance or pain at the site of intravenous injection, it is recommended to administer Neovir together with 2 ml of 0.25-0.5% novocaine solution.

Contraindications

Hypersensitivity, chronic renal failure degree II-III, pregnancy, lactation, childhood.

Side effects

General reactions: subfebrile fever, allergic reactions.

Local reactions: local, quickly resolving soreness at the site of injection.