Nasol, spray 0.025 mcg/dose 10 ml

Indications

To facilitate nasal breathing when:
— colds and viral infections of the upper respiratory tract
— sinusitis and rhinitis of any etiology.

Pharmacological effect

Pharmaceutical group:

anticongestive agent – vasoconstrictor (alpha-adrenergic agonist).

Pharmaceutical action:

Nazol is an alpha-adrenergic stimulant for topical use.

Oxymetazoline belongs to the group of alpha-agonists for topical use. Has a vasoconstrictor effect.

When administered intranasally, it reduces swelling of the mucous membrane of the upper respiratory tract, which leads to easier nasal breathing and the opening of the mouths of the paranasal sinuses and eustachian tubes.

The effect of the drug appears 10-15 minutes after application and lasts for 10-12 hours.

Special instructions

Use the recommended dosage without consulting a doctor for more than 3 days.

Avoid getting the drug into your eyes.

To avoid the spread of infection, it is necessary to use the drug individually.

Active ingredient

Oxymetazoline

Composition

1 ml:
– oxymetazoline hydrochloride 500 mcg

Excipients:

benzalkonium chloride (50% solution),

benzyl alcohol,

disodium edetate,

macrogol 400,

povidone,

propylene glycol,

sodium hydrogen phosphate,

sodium dihydrogen phosphate,

purified water.

Contraindications

– hypersensitivity to the drug Nazol or its components;
— atrophic rhinitis;
– children up to 6 years of age;
— pregnancy;
– lactation period.

The drug Nazol should be used with caution in patients suffering from diseases of the cardiovascular system (arterial hypertension, coronary artery disease, chronic heart failure, tachycardia, arrhythmias), disorders of carbohydrate metabolism (diabetes mellitus), thyroid function (hyperthyroidism), pheochromocytoma, chronic renal failure, prostatic hyperplasia (urinary retention) and closed-angle glaucoma, taking MAO inhibitors, tricyclic antidepressants.

Side Effects

Sometimes burning or dryness of the nasal membranes, dry mouth and throat, sneezing, increased volume of secretions released from the nose.

In rare cases, after the effect of using the drug wears off, a strong feeling of “stuffiness” in the nose (reactive hyperemia).

Side effects caused by the systemic action of the drug: increased blood pressure, headache, dizziness, palpitations, increased anxiety, nausea, insomnia.

With long-term use of the drug Nazol (more than 7 days), the following are possible: reactive hyperemia of the nasal mucosa, atrophy of the nasal mucosa, tachyphylaxis (rapid decrease in the therapeutic effect with repeated use).

Interaction

When Nazol is used simultaneously with MAO inhibitors (including a period of 14 days after their discontinuation) and tricyclic antidepressants, an increase in blood pressure may be observed.

The drug slows down the absorption of local anesthetic drugs and prolongs their effect.

Co-administration of other vasoconstrictor drugs increases the risk of side effects.

Overdose

Long-term or frequent use of the drug Nazol in the nasal cavity can cause nausea, increased blood pressure, tachycardia, and central nervous system depression.

Treatment is symptomatic.

Storage conditions

In a place protected from light, at a temperature not exceeding 25°C.

Shelf life

3 years.

Manufacturer

Instituto de Angeli S.r.L., Italy