Nanotropil Novo, tablets 100 mg 10 pcs
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Nootropic drug with a pronounced anti-amnesic effect, has a direct activating effect on integrative activity of the brain, promotes memory consolidation, improves attention concentration and mental performance, facilitates learning, increases the speed of information transfer between the cerebral hemispheres and resistance of brain tissue to toxic effects, has anticonvulsant effect and anxiolytic activity.
It has a positive effect on metabolic processes, stimulates Increases norepinephrine, dopamine and serotonin content in the brain, does not affect the level of GABA, does not bind with GABA and GABA receptors, does not affect spontaneous bioelectrical activity of the brain.
It has no effect on respiration and cardiovascular system, shows unremarkable diuretic effect, has anorexigenic activity during a course of use.
The stimulating effect is manifested by the ability to produce a moderately pronounced effect on motor reactions, increased physical performance, and weakening of the sleeping effect of ethanol and hexobarbital.
Psychostimulant effect prevails in the ideational sphere.
Moderate psychostimulant effect of the drug is combined with anxiolytic activity. It has some analgesic effect by increasing the threshold of pain sensitivity.
Adaptogenic effect is manifested by increased resistance to stress in conditions of excessive mental and physical exertion, fatigue, hypokinesia and immobilization, at low temperatures.
Against the background of the drug is noted improvement of vision, which is manifested in increased acuity, brightness and visual fields.
Improves blood supply to the lower extremities.
Stimulates the production of antibodies in response to antigen introduction, which indicates immunostimulating properties, but at the same time it does not contribute to the development of immediate hypersensitivity and does not change the allergic inflammatory skin reaction caused by the introduction of a foreign protein.
The action is observed during a single dose, which is important when using the drug in extreme conditions.
Absorption: It is quickly absorbed. Absolute bioavailability with oral administration is 100%.
Distribution: It penetrates into various organs and tissues, easily passes through the blood-brain barrier. Maximal concentration in blood (Tmax) is reached after 1 hour.
Metabolism: Not metabolized in the body.
Elimation: Half-life period (T1/2) – 3-5 hours. It is excreted unchanged: about 40% – by kidneys and 60% – in bile and sweat.
Indications
CNS diseases of various genesis, especially those associated with disorders of metabolic processes in the brain, intoxication (in particular, in post-traumatic states), accompanied by deterioration of intellectual and mental functions, decreased motor activity;
– Neurotic conditions manifested by lethargy, increased exhaustion, impaired attention, memory loss. – Neurotic conditions, manifested by lethargy, increased exhaustion, decreased psychomotor activity, impaired attention, memory impairment
– Learning disorders;
– Psycho-organic syndromes, manifested by intellectual and mental disorders and apathy and abulic phenomena and also apathy in schizophrenia;
– Convulsive conditions;
– Obesity (of alimentary and constitutional genesis);
– Prevention of hypoxia, stress resistance increase, correction of the organism functional condition in extreme conditions of professional activity aimed at prevention of fatigue and increase of mental and physical efficiency, correction of daily biorhythm, sleep-wake cycle inversion;
– Chronic alcoholism (in order to decrease intellectual and mental disorders).
Active ingredient
Fonturacetam
Composition
1 tablet contains:
The active ingredient: fonturacetam – 50.00 mg or 100.00 mg;
auxiliary substances: povidone K-17, microcrystalline cellulose, sodium carboxy-methyl starch, magnesium stearate.
How to take, the dosage
Ingestion. Take immediately after meals. The dose and duration of treatment should be determined by the doctor. Doses vary depending on the characteristics of the patient’s condition. The average single dose is 150 mg (100 to 250 mg); the average daily dose is 250 mg (200 to 300 mg). Maximum daily dose of Nanotropil® Novo is 750 mg. It is recommended that a daily dose of up to 100 mg should be taken once in the morning, and over 100 mg should be divided into 2 doses. The duration of treatment may vary from 2 weeks to 3 months, on average 30 days. If necessary, the course may be repeated after 1 month.
To improve performance, 100-200 mg once in the morning hours, for 2 weeks (for athletes, 3 days).
The recommended duration of therapy with the drug in patients with alimentary-constitutional obesity is 30-60 days in a dose of 100-200 mg once a day (in the morning hours). It is not recommended to take the drug later than 15 h.
Interaction
Fonturacetam can increase the effect of CNS stimulating drugs and nootropic drugs.
The drug shows pronounced antagonism to the cataleptic action of neuroleptics, and also weakens the severity of the sleeping effects of ethanol and hexobarbital.
Special Instructions
In excessive psycho-emotional exhaustion on the background of stress and fatigue, chronic insomnia, a single dose of the drug in the first day may cause a sharp need for sleep. It should be recommended to start course administration of the drug on non-working days for such patients in outpatient conditions.
Synopsis
Round flat cylindrical white to white with a yellowish tint, beveled for 50 mg dosage and beveled and boxed for 100 mg dosage.
Contraindications
Hypersensitivity to Fonturacetam or any excipient of the drug.
Pregnancy and breast-feeding.
Above 18 years of age (due to lack of clinical data on the efficacy and safety of use of Fonturacetam in this age population).
Side effects
Insomnia (in case of taking the drug later than 15 h). In some patients during the first 1-3 days of use psychomotor agitation, skin hyperemia, feeling of warmth, increased blood pressure are possible.
Overdose
No cases of overdose have been reported.
Treatment: symptomatic therapy.
Pregnancy use
There are no data on randomized clinical trials of Fonturacetam in pregnant women, therefore, the use of Nanotropil® Novo during pregnancy and breastfeeding is contraindicated.
Similarities
Phenotropil
Weight | 0.013 kg |
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Shelf life | 3 years. |
Conditions of storage | In the dark place at the temperature not more than 30 °С. Keep out of reach of children. |
Manufacturer | Obninsk HFC, Russia |
Medication form | pills |
Brand | Obninsk HFC |
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